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Gene: TUG1 |
Gene summary for TUG1 |
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Gene information | Species | Human | Gene symbol | TUG1 | Gene ID | 55000 |
Gene name | taurine up-regulated 1 | |
Gene Alias | LINC00080 | |
Cytomap | 22q12.2 | |
Gene Type | ncRNA | GO ID | GO:0001654 | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
55000 | TUG1 | HTA11_3410_2000001011 | Human | Colorectum | AD | 1.83e-02 | 9.21e-02 | 0.0155 |
55000 | TUG1 | HTA11_2487_2000001011 | Human | Colorectum | SER | 2.17e-11 | 3.32e-01 | -0.1808 |
55000 | TUG1 | HTA11_1938_2000001011 | Human | Colorectum | AD | 6.92e-17 | 4.31e-01 | -0.0811 |
55000 | TUG1 | HTA11_78_2000001011 | Human | Colorectum | AD | 5.43e-34 | 7.30e-01 | -0.1088 |
55000 | TUG1 | HTA11_347_2000001011 | Human | Colorectum | AD | 3.98e-31 | 5.54e-01 | -0.1954 |
55000 | TUG1 | HTA11_2112_2000001011 | Human | Colorectum | SER | 1.71e-03 | 2.76e-01 | -0.2196 |
55000 | TUG1 | HTA11_3361_2000001011 | Human | Colorectum | AD | 2.22e-02 | 1.46e-01 | -0.1207 |
55000 | TUG1 | HTA11_83_2000001011 | Human | Colorectum | SER | 7.80e-11 | 3.83e-01 | -0.1526 |
55000 | TUG1 | HTA11_696_2000001011 | Human | Colorectum | AD | 2.83e-15 | 2.65e-01 | -0.1464 |
55000 | TUG1 | HTA11_866_2000001011 | Human | Colorectum | AD | 7.82e-13 | 2.28e-01 | -0.1001 |
55000 | TUG1 | HTA11_1391_2000001011 | Human | Colorectum | AD | 6.11e-08 | 2.44e-01 | -0.059 |
55000 | TUG1 | HTA11_2992_2000001011 | Human | Colorectum | SER | 1.53e-17 | 7.14e-01 | -0.1706 |
55000 | TUG1 | HTA11_5212_2000001011 | Human | Colorectum | AD | 5.12e-05 | 2.80e-01 | -0.2061 |
55000 | TUG1 | HTA11_5216_2000001011 | Human | Colorectum | SER | 3.22e-05 | 3.63e-01 | -0.1462 |
55000 | TUG1 | HTA11_546_2000001011 | Human | Colorectum | AD | 1.74e-13 | 4.42e-01 | -0.0842 |
55000 | TUG1 | HTA11_9341_2000001011 | Human | Colorectum | SER | 4.01e-04 | 3.31e-01 | -0.00410000000000005 |
55000 | TUG1 | HTA11_7862_2000001011 | Human | Colorectum | AD | 1.67e-07 | 4.04e-01 | -0.0179 |
55000 | TUG1 | HTA11_866_3004761011 | Human | Colorectum | AD | 9.64e-19 | 4.25e-01 | 0.096 |
55000 | TUG1 | HTA11_4255_2000001011 | Human | Colorectum | SER | 3.40e-02 | 2.52e-01 | 0.0446 |
55000 | TUG1 | HTA11_8622_2000001021 | Human | Colorectum | SER | 6.14e-04 | 2.67e-01 | 0.0528 |
Page: 1 2 3 4 5 6 7 8 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:0045664 | Prostate | BPH | regulation of neuron differentiation | 46/3107 | 196/18723 | 7.95e-03 | 3.47e-02 | 46 |
GO:00456641 | Prostate | Tumor | regulation of neuron differentiation | 52/3246 | 196/18723 | 7.90e-04 | 5.38e-03 | 52 |
GO:00016541 | Prostate | Tumor | eye development | 82/3246 | 371/18723 | 1.02e-02 | 4.27e-02 | 82 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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