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Gene: TPRXL |
Gene summary for TPRXL |
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Gene information | Species | Human | Gene symbol | TPRXL | Gene ID | 348825 |
Gene name | tetrapeptide repeat homeobox like (pseudogene) | |
Gene Alias | TPRX3P | |
Cytomap | 3p25.1 | |
Gene Type | pseudo | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
348825 | TPRXL | P1T-E | Human | Esophagus | ESCC | 2.96e-03 | 1.41e-01 | 0.0875 |
348825 | TPRXL | P2T-E | Human | Esophagus | ESCC | 2.94e-06 | 8.28e-02 | 0.1177 |
348825 | TPRXL | P4T-E | Human | Esophagus | ESCC | 6.10e-08 | 1.99e-01 | 0.1323 |
348825 | TPRXL | P5T-E | Human | Esophagus | ESCC | 9.46e-07 | 1.26e-01 | 0.1327 |
348825 | TPRXL | P9T-E | Human | Esophagus | ESCC | 7.49e-06 | 1.52e-01 | 0.1131 |
348825 | TPRXL | P11T-E | Human | Esophagus | ESCC | 2.25e-02 | 1.69e-01 | 0.1426 |
348825 | TPRXL | P15T-E | Human | Esophagus | ESCC | 4.30e-08 | 8.15e-02 | 0.1149 |
348825 | TPRXL | P20T-E | Human | Esophagus | ESCC | 1.58e-25 | 5.89e-01 | 0.1124 |
348825 | TPRXL | P21T-E | Human | Esophagus | ESCC | 1.07e-04 | 1.32e-01 | 0.1617 |
348825 | TPRXL | P23T-E | Human | Esophagus | ESCC | 5.93e-10 | 1.18e-01 | 0.108 |
348825 | TPRXL | P24T-E | Human | Esophagus | ESCC | 4.48e-06 | 1.74e-01 | 0.1287 |
348825 | TPRXL | P27T-E | Human | Esophagus | ESCC | 2.56e-09 | 2.07e-01 | 0.1055 |
348825 | TPRXL | P28T-E | Human | Esophagus | ESCC | 4.37e-14 | 3.24e-01 | 0.1149 |
348825 | TPRXL | P30T-E | Human | Esophagus | ESCC | 7.11e-20 | 6.66e-01 | 0.137 |
348825 | TPRXL | P31T-E | Human | Esophagus | ESCC | 6.04e-06 | 1.19e-01 | 0.1251 |
348825 | TPRXL | P32T-E | Human | Esophagus | ESCC | 4.67e-02 | 1.34e-01 | 0.1666 |
348825 | TPRXL | P36T-E | Human | Esophagus | ESCC | 1.85e-05 | 2.32e-01 | 0.1187 |
348825 | TPRXL | P37T-E | Human | Esophagus | ESCC | 3.30e-04 | 4.22e-02 | 0.1371 |
348825 | TPRXL | P40T-E | Human | Esophagus | ESCC | 1.53e-05 | 1.99e-01 | 0.109 |
348825 | TPRXL | P42T-E | Human | Esophagus | ESCC | 4.11e-04 | 1.37e-01 | 0.1175 |
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Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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