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Gene: TMEM238L |
Gene summary for TMEM238L |
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Gene information | Species | Human | Gene symbol | TMEM238L | Gene ID | 100289255 |
Gene name | transmembrane protein 238 like | |
Gene Alias | FORCP | |
Cytomap | 17p13.1-p12 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100289255 | TMEM238L | HTA11_347_2000001011 | Human | Colorectum | AD | 4.88e-17 | 6.33e-01 | -0.1954 |
100289255 | TMEM238L | HTA11_5212_2000001011 | Human | Colorectum | AD | 2.05e-06 | 6.90e-01 | -0.2061 |
100289255 | TMEM238L | HTA11_99999970781_79442 | Human | Colorectum | MSS | 3.83e-12 | -2.58e-01 | 0.294 |
100289255 | TMEM238L | HTA11_99999965104_69814 | Human | Colorectum | MSS | 4.53e-02 | -2.58e-01 | 0.281 |
100289255 | TMEM238L | HTA11_99999971662_82457 | Human | Colorectum | MSS | 7.11e-14 | -2.58e-01 | 0.3859 |
100289255 | TMEM238L | HTA11_99999974143_84620 | Human | Colorectum | MSS | 7.11e-14 | -2.58e-01 | 0.3005 |
100289255 | TMEM238L | A002-C-010 | Human | Colorectum | FAP | 2.43e-02 | -1.55e-01 | 0.242 |
100289255 | TMEM238L | A015-C-203 | Human | Colorectum | FAP | 5.17e-06 | -1.85e-01 | -0.1294 |
100289255 | TMEM238L | A002-C-201 | Human | Colorectum | FAP | 6.93e-03 | -2.04e-01 | 0.0324 |
100289255 | TMEM238L | A002-C-203 | Human | Colorectum | FAP | 7.99e-03 | -1.73e-01 | 0.2786 |
100289255 | TMEM238L | A001-C-108 | Human | Colorectum | FAP | 5.36e-06 | -1.86e-01 | -0.0272 |
100289255 | TMEM238L | A002-C-205 | Human | Colorectum | FAP | 1.44e-04 | -2.17e-01 | -0.1236 |
100289255 | TMEM238L | A001-C-104 | Human | Colorectum | FAP | 1.08e-02 | -1.69e-01 | 0.0184 |
100289255 | TMEM238L | A015-C-006 | Human | Colorectum | FAP | 8.03e-05 | -2.58e-01 | -0.0994 |
100289255 | TMEM238L | A015-C-106 | Human | Colorectum | FAP | 1.60e-03 | -1.68e-01 | -0.0511 |
100289255 | TMEM238L | A002-C-114 | Human | Colorectum | FAP | 2.98e-03 | -2.04e-01 | -0.1561 |
100289255 | TMEM238L | A015-C-104 | Human | Colorectum | FAP | 1.34e-09 | -2.34e-01 | -0.1899 |
100289255 | TMEM238L | A001-C-014 | Human | Colorectum | FAP | 1.14e-05 | -1.83e-01 | 0.0135 |
100289255 | TMEM238L | A002-C-016 | Human | Colorectum | FAP | 8.48e-09 | -2.17e-01 | 0.0521 |
100289255 | TMEM238L | A001-C-203 | Human | Colorectum | FAP | 1.40e-05 | -1.88e-01 | -0.0481 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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