![]() |
|||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: TLNRD1 |
Gene summary for TLNRD1 |
![]() |
Gene information | Species | Human | Gene symbol | TLNRD1 | Gene ID | 59274 |
Gene name | talin rod domain containing 1 | |
Gene Alias | MESDC1 | |
Cytomap | 15q25.1 | |
Gene Type | protein-coding | GO ID | GO:0001725 | UniProtAcc | Q9H1K6 |
Top |
Malignant transformation analysis |
![]() |
![]() |
Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
59274 | TLNRD1 | S015 | Human | Liver | HCC | 1.55e-02 | 2.33e-01 | 0.2375 |
59274 | TLNRD1 | S027 | Human | Liver | HCC | 4.26e-11 | 6.49e-01 | 0.2446 |
59274 | TLNRD1 | S028 | Human | Liver | HCC | 1.68e-20 | 6.71e-01 | 0.2503 |
59274 | TLNRD1 | S029 | Human | Liver | HCC | 3.51e-10 | 4.39e-01 | 0.2581 |
59274 | TLNRD1 | male-WTA | Human | Thyroid | PTC | 1.28e-06 | 1.26e-01 | 0.1037 |
59274 | TLNRD1 | PTC04 | Human | Thyroid | PTC | 5.14e-03 | 9.28e-02 | 0.1927 |
59274 | TLNRD1 | PTC06 | Human | Thyroid | PTC | 1.69e-04 | 1.89e-01 | 0.2057 |
59274 | TLNRD1 | PTC07 | Human | Thyroid | PTC | 2.77e-07 | 1.60e-01 | 0.2044 |
59274 | TLNRD1 | ATC09 | Human | Thyroid | ATC | 1.54e-13 | 3.68e-01 | 0.2871 |
59274 | TLNRD1 | ATC11 | Human | Thyroid | ATC | 7.49e-03 | 2.94e-01 | 0.3386 |
59274 | TLNRD1 | ATC12 | Human | Thyroid | ATC | 1.90e-14 | 3.36e-01 | 0.34 |
59274 | TLNRD1 | ATC13 | Human | Thyroid | ATC | 1.85e-30 | 5.68e-01 | 0.34 |
59274 | TLNRD1 | ATC1 | Human | Thyroid | ATC | 1.33e-13 | 3.97e-01 | 0.2878 |
59274 | TLNRD1 | ATC2 | Human | Thyroid | ATC | 5.35e-04 | 4.38e-01 | 0.34 |
59274 | TLNRD1 | ATC4 | Human | Thyroid | ATC | 8.26e-18 | 4.10e-01 | 0.34 |
59274 | TLNRD1 | ATC5 | Human | Thyroid | ATC | 3.04e-38 | 6.20e-01 | 0.34 |
Page: 1 |
![]() |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
Top |
Malignant transformation related pathway analysis |
![]() |
![]() |
Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
![]() |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
![]() |
Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
Top |
Cell-cell communication analysis |
![]() |
Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
Top |
Single-cell gene regulatory network inference analysis |
![]() |
TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
Top |
Somatic mutation of malignant transformation related genes |
![]() |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
Top |
Related drugs of malignant transformation related genes |
![]() |
(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |