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Gene: TEX29 |
Gene summary for TEX29 |
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Gene information | Species | Human | Gene symbol | TEX29 | Gene ID | 121793 |
Gene name | testis expressed 29 | |
Gene Alias | C13orf16 | |
Cytomap | 13q34 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | Q8N6K0 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
121793 | TEX29 | ATC2 | Human | Thyroid | ATC | 9.94e-09 | 1.13e+00 | 0.34 |
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Tissue | Expression Dynamics | Abbreviation |
Thyroid | ![]() | ATC: Anaplastic thyroid cancer |
HT: Hashimoto's thyroiditis | ||
PTC: Papillary thyroid cancer |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
TEX29 | insertion | In_Frame_Ins | novel | c.372_373insCCATCAGAGTCATTCAGG | p.Pro124_Ser125insProSerGluSerPheArg | p.P124_S125insPSESFR | Q8N6K0 | protein_coding | TCGA-AO-A0JD-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Chemotherapy | cyclophosphamide | SD | ||
TEX29 | insertion | Frame_Shift_Ins | novel | c.229_230insACAG | p.Ile77AsnfsTer58 | p.I77Nfs*58 | Q8N6K0 | protein_coding | TCGA-B6-A0IB-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | PD | ||
TEX29 | insertion | Nonsense_Mutation | novel | c.231_232insCTCACTTAAAGAAATAAGGCAGCTGATTGGAAGAATGTTTG | p.Ile78LeufsTer3 | p.I78Lfs*3 | Q8N6K0 | protein_coding | TCGA-B6-A0IB-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | PD | ||
TEX29 | SNV | Missense_Mutation | rs375512703 | c.161N>T | p.Ala54Val | p.A54V | Q8N6K0 | protein_coding | tolerated(0.08) | benign(0.316) | TCGA-AA-3947-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
TEX29 | SNV | Missense_Mutation | c.84T>G | p.Ile28Met | p.I28M | Q8N6K0 | protein_coding | deleterious(0) | possibly_damaging(0.79) | TCGA-AG-A002-01 | Colorectum | rectum adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | SD | |
TEX29 | insertion | Frame_Shift_Ins | novel | c.157_158insACCTGGG | p.Lys53AsnfsTer83 | p.K53Nfs*83 | Q8N6K0 | protein_coding | TCGA-AM-5820-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD | ||
TEX29 | SNV | Missense_Mutation | novel | c.362N>A | p.Pro121His | p.P121H | Q8N6K0 | protein_coding | tolerated_low_confidence(0.14) | benign(0.184) | TCGA-AJ-A3EK-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Chemotherapy | carboplatin | CR |
TEX29 | SNV | Missense_Mutation | rs199521485 | c.208N>A | p.Ala70Thr | p.A70T | Q8N6K0 | protein_coding | tolerated(0.1) | benign(0.342) | TCGA-AJ-A3OJ-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Chemotherapy | carboplatin | CR |
TEX29 | SNV | Missense_Mutation | rs757375604 | c.10N>A | p.Val4Met | p.V4M | Q8N6K0 | protein_coding | tolerated(0.17) | benign(0.03) | TCGA-AX-A0J1-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
TEX29 | SNV | Missense_Mutation | novel | c.242T>C | p.Val81Ala | p.V81A | Q8N6K0 | protein_coding | tolerated(0.12) | benign(0.018) | TCGA-AX-A2HD-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | III/IV | Unknown | Unknown | SD |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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