![]() |
|||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: SREBF2-AS1 |
Gene summary for SREBF2-AS1 |
![]() |
Gene information | Species | Human | Gene symbol | SREBF2-AS1 | Gene ID | 112637020 |
Gene name | SREBF2 antisense RNA 1 | |
Gene Alias | 821D11.7 | |
Cytomap | 22q13.2 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
Top |
Malignant transformation analysis |
![]() |
![]() |
Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
112637020 | SREBF2-AS1 | LZE4T | Human | Esophagus | ESCC | 2.18e-06 | 2.32e-01 | 0.0811 |
112637020 | SREBF2-AS1 | LZE7T | Human | Esophagus | ESCC | 1.02e-03 | 1.95e-01 | 0.0667 |
112637020 | SREBF2-AS1 | LZE8T | Human | Esophagus | ESCC | 4.02e-05 | 1.67e-01 | 0.067 |
112637020 | SREBF2-AS1 | LZE20T | Human | Esophagus | ESCC | 4.98e-02 | 1.19e-01 | 0.0662 |
112637020 | SREBF2-AS1 | LZE21D1 | Human | Esophagus | HGIN | 2.08e-07 | 6.78e-01 | 0.0632 |
112637020 | SREBF2-AS1 | LZE22T | Human | Esophagus | ESCC | 1.57e-02 | 2.52e-01 | 0.068 |
112637020 | SREBF2-AS1 | LZE24T | Human | Esophagus | ESCC | 2.20e-04 | 1.35e-01 | 0.0596 |
112637020 | SREBF2-AS1 | LZE21T | Human | Esophagus | ESCC | 2.35e-12 | 7.59e-01 | 0.0655 |
Page: 1 |
![]() |
Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
Top |
Malignant transformation related pathway analysis |
![]() |
![]() |
Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
![]() |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
![]() |
Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
Top |
Cell-cell communication analysis |
![]() |
Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
Top |
Single-cell gene regulatory network inference analysis |
![]() |
TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
Top |
Somatic mutation of malignant transformation related genes |
![]() |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
Top |
Related drugs of malignant transformation related genes |
![]() |
(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |