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Gene: SNAP25-AS1 |
Gene summary for SNAP25-AS1 |
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Gene information | Species | Human | Gene symbol | SNAP25-AS1 | Gene ID | 100131208 |
Gene name | SNAP25 antisense RNA 1 | |
Gene Alias | SNAP25-AS1 | |
Cytomap | 20p12.2 | |
Gene Type | ncRNA | GO ID | GO:0006605 | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100131208 | SNAP25-AS1 | HCC2 | Human | Liver | HCC | 1.62e-03 | 5.38e-01 | 0.5341 |
100131208 | SNAP25-AS1 | S027 | Human | Liver | HCC | 1.44e-02 | 4.44e-01 | 0.2446 |
100131208 | SNAP25-AS1 | S028 | Human | Liver | HCC | 1.01e-12 | 6.75e-01 | 0.2503 |
100131208 | SNAP25-AS1 | S029 | Human | Liver | HCC | 3.25e-04 | 3.41e-01 | 0.2581 |
100131208 | SNAP25-AS1 | HTA12-15-2 | Human | Pancreas | PDAC | 4.27e-03 | 2.82e-01 | 0.2315 |
100131208 | SNAP25-AS1 | HTA12-25-1 | Human | Pancreas | PDAC | 3.52e-06 | 4.23e-01 | 0.313 |
100131208 | SNAP25-AS1 | HTA12-26-1 | Human | Pancreas | PDAC | 7.59e-10 | 5.29e-01 | 0.3728 |
100131208 | SNAP25-AS1 | HTA12-29-1 | Human | Pancreas | PDAC | 1.40e-31 | 6.49e-01 | 0.3722 |
100131208 | SNAP25-AS1 | HTA12-32-1 | Human | Pancreas | PDAC | 4.65e-02 | 5.17e-01 | 0.3624 |
100131208 | SNAP25-AS1 | HTA12-9-1 | Human | Pancreas | PDAC | 1.43e-06 | 5.27e-01 | 0.1532 |
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Tissue | Expression Dynamics | Abbreviation |
Liver | ![]() | HCC: Hepatocellular carcinoma |
NAFLD: Non-alcoholic fatty liver disease |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:007259422 | Liver | HCC | establishment of protein localization to organelle | 299/7958 | 422/18723 | 1.06e-32 | 6.10e-30 | 299 |
GO:000660512 | Liver | HCC | protein targeting | 219/7958 | 314/18723 | 7.74e-23 | 1.49e-20 | 219 |
GO:009015012 | Liver | HCC | establishment of protein localization to membrane | 168/7958 | 260/18723 | 4.07e-13 | 2.13e-11 | 168 |
GO:007097212 | Liver | HCC | protein localization to endoplasmic reticulum | 54/7958 | 74/18723 | 1.01e-07 | 1.98e-06 | 54 |
GO:007259911 | Liver | HCC | establishment of protein localization to endoplasmic reticulum | 34/7958 | 46/18723 | 1.53e-05 | 1.67e-04 | 34 |
GO:004504711 | Liver | HCC | protein targeting to ER | 30/7958 | 42/18723 | 1.40e-04 | 1.13e-03 | 30 |
GO:00066121 | Liver | HCC | protein targeting to membrane | 75/7958 | 131/18723 | 4.58e-04 | 3.04e-03 | 75 |
GO:00066131 | Liver | HCC | cotranslational protein targeting to membrane | 20/7958 | 31/18723 | 1.11e-02 | 4.09e-02 | 20 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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