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Gene: SMIM26 |
Gene summary for SMIM26 |
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Gene information | Species | Human | Gene symbol | SMIM26 | Gene ID | 388789 |
Gene name | small integral membrane protein 26 | |
Gene Alias | LINC00493 | |
Cytomap | 20p11.23 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
388789 | SMIM26 | GSM4909281 | Human | Breast | IDC | 1.43e-02 | 2.90e-01 | 0.21 |
388789 | SMIM26 | GSM4909285 | Human | Breast | IDC | 1.51e-09 | 2.29e-01 | 0.21 |
388789 | SMIM26 | GSM4909286 | Human | Breast | IDC | 7.19e-12 | 2.17e-01 | 0.1081 |
388789 | SMIM26 | GSM4909290 | Human | Breast | IDC | 3.68e-02 | 2.26e-01 | 0.2096 |
388789 | SMIM26 | GSM4909291 | Human | Breast | IDC | 5.86e-03 | 4.06e-01 | 0.1753 |
388789 | SMIM26 | GSM4909293 | Human | Breast | IDC | 1.45e-02 | 4.97e-02 | 0.1581 |
388789 | SMIM26 | GSM4909297 | Human | Breast | IDC | 3.03e-04 | 1.36e-01 | 0.1517 |
388789 | SMIM26 | GSM4909298 | Human | Breast | IDC | 8.85e-19 | 5.60e-01 | 0.1551 |
388789 | SMIM26 | GSM4909299 | Human | Breast | IDC | 1.31e-06 | 4.20e-01 | 0.035 |
388789 | SMIM26 | GSM4909301 | Human | Breast | IDC | 3.84e-02 | 3.33e-01 | 0.1577 |
388789 | SMIM26 | GSM4909304 | Human | Breast | IDC | 1.88e-04 | -2.59e-01 | 0.1636 |
388789 | SMIM26 | GSM4909305 | Human | Breast | IDC | 1.85e-05 | 3.36e-01 | 0.0436 |
388789 | SMIM26 | GSM4909306 | Human | Breast | IDC | 1.55e-05 | 3.30e-01 | 0.1564 |
388789 | SMIM26 | GSM4909308 | Human | Breast | IDC | 3.23e-13 | 3.84e-01 | 0.158 |
388789 | SMIM26 | GSM4909309 | Human | Breast | IDC | 4.71e-02 | 3.49e-01 | 0.0483 |
388789 | SMIM26 | GSM4909311 | Human | Breast | IDC | 1.81e-30 | 2.61e-01 | 0.1534 |
388789 | SMIM26 | GSM4909312 | Human | Breast | IDC | 5.74e-08 | 2.69e-01 | 0.1552 |
388789 | SMIM26 | GSM4909317 | Human | Breast | IDC | 3.83e-26 | 7.36e-01 | 0.1355 |
388789 | SMIM26 | GSM4909318 | Human | Breast | IDC | 1.30e-12 | 8.08e-01 | 0.2031 |
388789 | SMIM26 | GSM4909319 | Human | Breast | IDC | 1.05e-31 | -2.07e-01 | 0.1563 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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