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Gene: SEPP1 |
Gene summary for SEPP1 |
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Gene information | Species | Human | Gene symbol | SEPP1 | Gene ID | 6414 |
Gene name | selenoprotein P | |
Gene Alias | SELP | |
Cytomap | 5p12 | |
Gene Type | protein-coding | GO ID | GO:0000003 | UniProtAcc | P49908 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
6414 | SEPP1 | AEH-subject1 | Human | Endometrium | AEH | 1.03e-53 | -7.64e-01 | -0.3059 |
6414 | SEPP1 | AEH-subject2 | Human | Endometrium | AEH | 1.37e-43 | -7.64e-01 | -0.2525 |
6414 | SEPP1 | AEH-subject3 | Human | Endometrium | AEH | 3.40e-54 | -7.64e-01 | -0.2576 |
6414 | SEPP1 | AEH-subject4 | Human | Endometrium | AEH | 2.98e-34 | -7.64e-01 | -0.2657 |
6414 | SEPP1 | AEH-subject5 | Human | Endometrium | AEH | 3.40e-54 | -7.64e-01 | -0.2953 |
6414 | SEPP1 | EEC-subject1 | Human | Endometrium | EEC | 9.30e-53 | -7.64e-01 | -0.2682 |
6414 | SEPP1 | EEC-subject2 | Human | Endometrium | EEC | 1.12e-54 | -7.64e-01 | -0.2607 |
6414 | SEPP1 | EEC-subject3 | Human | Endometrium | EEC | 1.19e-55 | -7.64e-01 | -0.2525 |
6414 | SEPP1 | EEC-subject4 | Human | Endometrium | EEC | 3.66e-55 | -7.64e-01 | -0.2571 |
6414 | SEPP1 | EEC-subject5 | Human | Endometrium | EEC | 4.01e-57 | -7.64e-01 | -0.249 |
6414 | SEPP1 | GSM5276934 | Human | Endometrium | EEC | 1.19e-55 | -7.64e-01 | -0.0913 |
6414 | SEPP1 | GSM5276935 | Human | Endometrium | EEC | 3.66e-55 | -7.64e-01 | -0.123 |
6414 | SEPP1 | GSM5276937 | Human | Endometrium | EEC | 3.85e-41 | -7.64e-01 | -0.0897 |
6414 | SEPP1 | GSM6177620_NYU_UCEC1_lib1_lib1 | Human | Endometrium | EEC | 4.37e-36 | -7.64e-01 | -0.1869 |
6414 | SEPP1 | GSM6177620_NYU_UCEC1_lib2_lib2 | Human | Endometrium | EEC | 2.31e-32 | -7.64e-01 | -0.1875 |
6414 | SEPP1 | GSM6177620_NYU_UCEC1_lib3_lib3 | Human | Endometrium | EEC | 2.81e-37 | -7.64e-01 | -0.1883 |
6414 | SEPP1 | GSM6177621_NYU_UCEC2_lib1_lib1 | Human | Endometrium | EEC | 9.30e-53 | -7.64e-01 | -0.1934 |
6414 | SEPP1 | GSM6177622_NYU_UCEC3_lib1_lib1 | Human | Endometrium | EEC | 9.30e-53 | -7.64e-01 | -0.1917 |
6414 | SEPP1 | GSM6177622_NYU_UCEC3_lib2_lib2 | Human | Endometrium | EEC | 1.83e-47 | -7.64e-01 | -0.1916 |
6414 | SEPP1 | GSM6177623_NYU_UCEC3_Vis | Human | Endometrium | EEC | 3.10e-53 | -7.64e-01 | -0.1269 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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