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Gene: SELO |
Gene summary for SELO |
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Gene information | Species | Human | Gene symbol | SELO | Gene ID | 83642 |
Gene name | selenoprotein O | |
Gene Alias | SELO | |
Cytomap | 22q13.33 | |
Gene Type | protein-coding | GO ID | GO:0006464 | UniProtAcc | Q9BVL4 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
83642 | SELO | P1T-E | Human | Esophagus | ESCC | 3.65e-18 | 6.00e-01 | 0.0875 |
83642 | SELO | P2T-E | Human | Esophagus | ESCC | 9.91e-17 | 3.74e-01 | 0.1177 |
83642 | SELO | P4T-E | Human | Esophagus | ESCC | 4.88e-15 | 3.52e-01 | 0.1323 |
83642 | SELO | P5T-E | Human | Esophagus | ESCC | 2.57e-16 | 2.45e-01 | 0.1327 |
83642 | SELO | P8T-E | Human | Esophagus | ESCC | 2.75e-23 | 3.63e-01 | 0.0889 |
83642 | SELO | P9T-E | Human | Esophagus | ESCC | 1.97e-11 | 3.10e-01 | 0.1131 |
83642 | SELO | P10T-E | Human | Esophagus | ESCC | 2.84e-15 | 2.64e-01 | 0.116 |
83642 | SELO | P11T-E | Human | Esophagus | ESCC | 8.17e-06 | 3.87e-01 | 0.1426 |
83642 | SELO | P12T-E | Human | Esophagus | ESCC | 1.01e-13 | 2.11e-01 | 0.1122 |
83642 | SELO | P15T-E | Human | Esophagus | ESCC | 1.68e-21 | 3.13e-01 | 0.1149 |
83642 | SELO | P16T-E | Human | Esophagus | ESCC | 2.90e-14 | 2.66e-01 | 0.1153 |
83642 | SELO | P17T-E | Human | Esophagus | ESCC | 4.11e-04 | 2.41e-01 | 0.1278 |
83642 | SELO | P21T-E | Human | Esophagus | ESCC | 6.39e-13 | 8.77e-02 | 0.1617 |
83642 | SELO | P22T-E | Human | Esophagus | ESCC | 6.71e-11 | 2.09e-01 | 0.1236 |
83642 | SELO | P23T-E | Human | Esophagus | ESCC | 1.59e-13 | 3.34e-01 | 0.108 |
83642 | SELO | P24T-E | Human | Esophagus | ESCC | 3.16e-11 | 2.80e-01 | 0.1287 |
83642 | SELO | P26T-E | Human | Esophagus | ESCC | 4.30e-17 | 4.38e-01 | 0.1276 |
83642 | SELO | P27T-E | Human | Esophagus | ESCC | 1.97e-07 | 1.90e-01 | 0.1055 |
83642 | SELO | P28T-E | Human | Esophagus | ESCC | 1.43e-07 | 9.96e-02 | 0.1149 |
83642 | SELO | P30T-E | Human | Esophagus | ESCC | 5.77e-22 | 6.12e-01 | 0.137 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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