![]() |
|||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: RNMTL1 |
Gene summary for RNMTL1 |
![]() |
Gene information | Species | Human | Gene symbol | RNMTL1 | Gene ID | 55178 |
Gene name | mitochondrial rRNA methyltransferase 3 | |
Gene Alias | RMTL1 | |
Cytomap | 17p13.3 | |
Gene Type | protein-coding | GO ID | GO:0000154 | UniProtAcc | Q9HC36 |
Top |
Malignant transformation analysis |
![]() |
![]() |
Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
55178 | RNMTL1 | P1T-E | Human | Esophagus | ESCC | 7.43e-09 | 3.31e-01 | 0.0875 |
55178 | RNMTL1 | P2T-E | Human | Esophagus | ESCC | 4.19e-25 | 4.47e-01 | 0.1177 |
55178 | RNMTL1 | P4T-E | Human | Esophagus | ESCC | 4.30e-23 | 4.86e-01 | 0.1323 |
55178 | RNMTL1 | P5T-E | Human | Esophagus | ESCC | 9.20e-06 | 1.46e-01 | 0.1327 |
55178 | RNMTL1 | P8T-E | Human | Esophagus | ESCC | 2.03e-09 | 1.77e-01 | 0.0889 |
55178 | RNMTL1 | P9T-E | Human | Esophagus | ESCC | 1.09e-13 | 3.14e-01 | 0.1131 |
55178 | RNMTL1 | P10T-E | Human | Esophagus | ESCC | 9.02e-11 | 2.26e-01 | 0.116 |
55178 | RNMTL1 | P11T-E | Human | Esophagus | ESCC | 6.08e-06 | 2.08e-01 | 0.1426 |
55178 | RNMTL1 | P12T-E | Human | Esophagus | ESCC | 4.19e-25 | 4.60e-01 | 0.1122 |
55178 | RNMTL1 | P15T-E | Human | Esophagus | ESCC | 7.07e-10 | 2.14e-01 | 0.1149 |
55178 | RNMTL1 | P16T-E | Human | Esophagus | ESCC | 3.58e-28 | 5.61e-01 | 0.1153 |
55178 | RNMTL1 | P17T-E | Human | Esophagus | ESCC | 1.49e-05 | 2.69e-01 | 0.1278 |
55178 | RNMTL1 | P19T-E | Human | Esophagus | ESCC | 4.64e-06 | 3.45e-01 | 0.1662 |
55178 | RNMTL1 | P20T-E | Human | Esophagus | ESCC | 1.39e-16 | 3.36e-01 | 0.1124 |
55178 | RNMTL1 | P21T-E | Human | Esophagus | ESCC | 1.85e-18 | 3.67e-01 | 0.1617 |
55178 | RNMTL1 | P22T-E | Human | Esophagus | ESCC | 1.46e-28 | 4.65e-01 | 0.1236 |
55178 | RNMTL1 | P23T-E | Human | Esophagus | ESCC | 2.12e-16 | 3.82e-01 | 0.108 |
55178 | RNMTL1 | P24T-E | Human | Esophagus | ESCC | 2.20e-17 | 3.44e-01 | 0.1287 |
55178 | RNMTL1 | P26T-E | Human | Esophagus | ESCC | 1.75e-25 | 3.97e-01 | 0.1276 |
55178 | RNMTL1 | P27T-E | Human | Esophagus | ESCC | 3.28e-14 | 3.25e-01 | 0.1055 |
Page: 1 2 3 4 |
![]() |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
Top |
Malignant transformation related pathway analysis |
![]() |
![]() |
Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
![]() |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
![]() |
Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
Top |
Cell-cell communication analysis |
![]() |
Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
Top |
Single-cell gene regulatory network inference analysis |
![]() |
TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
Top |
Somatic mutation of malignant transformation related genes |
![]() |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
Top |
Related drugs of malignant transformation related genes |
![]() |
(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |