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Gene: RFX3-AS1 |
Gene summary for RFX3-AS1 |
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Gene information | Species | Human | Gene symbol | RFX3-AS1 | Gene ID | 101929302 |
Gene name | RFX3 divergent transcript | |
Gene Alias | CVAT7 | |
Cytomap | 9p24.2 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
101929302 | RFX3-AS1 | AEH-subject1 | Human | Endometrium | AEH | 2.57e-15 | 3.42e-01 | -0.3059 |
101929302 | RFX3-AS1 | AEH-subject2 | Human | Endometrium | AEH | 3.08e-07 | 2.14e-01 | -0.2525 |
101929302 | RFX3-AS1 | AEH-subject3 | Human | Endometrium | AEH | 1.74e-13 | 3.48e-01 | -0.2576 |
101929302 | RFX3-AS1 | AEH-subject4 | Human | Endometrium | AEH | 3.20e-11 | 3.34e-01 | -0.2657 |
101929302 | RFX3-AS1 | EEC-subject1 | Human | Endometrium | EEC | 4.11e-04 | 1.87e-01 | -0.2682 |
101929302 | RFX3-AS1 | EEC-subject2 | Human | Endometrium | EEC | 6.98e-08 | 2.82e-01 | -0.2607 |
101929302 | RFX3-AS1 | EEC-subject4 | Human | Endometrium | EEC | 3.84e-03 | 1.78e-01 | -0.2571 |
101929302 | RFX3-AS1 | EEC-subject5 | Human | Endometrium | EEC | 8.70e-06 | 1.99e-01 | -0.249 |
101929302 | RFX3-AS1 | HTA12-15-2 | Human | Pancreas | PDAC | 4.41e-04 | 2.92e-01 | 0.2315 |
101929302 | RFX3-AS1 | HTA12-23-1 | Human | Pancreas | PDAC | 1.74e-14 | 9.34e-01 | 0.3405 |
101929302 | RFX3-AS1 | HTA12-25-1 | Human | Pancreas | PDAC | 7.61e-16 | 8.60e-01 | 0.313 |
101929302 | RFX3-AS1 | HTA12-26-1 | Human | Pancreas | PDAC | 1.81e-32 | 1.18e+00 | 0.3728 |
101929302 | RFX3-AS1 | HTA12-29-1 | Human | Pancreas | PDAC | 2.26e-39 | 8.27e-01 | 0.3722 |
101929302 | RFX3-AS1 | HTA12-30-1 | Human | Pancreas | PDAC | 2.27e-04 | 1.02e+00 | 0.3671 |
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Tissue | Expression Dynamics | Abbreviation |
Endometrium | ![]() | AEH: Atypical endometrial hyperplasia |
EEC: Endometrioid Cancer |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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