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Gene: RELCH |
Gene summary for RELCH |
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Gene information | Species | Human | Gene symbol | RELCH | Gene ID | 57614 |
Gene name | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | |
Gene Alias | HsT3308 | |
Cytomap | 18q21.33 | |
Gene Type | protein-coding | GO ID | GO:0006810 | UniProtAcc | Q9P260 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
57614 | RELCH | CCI_1 | Human | Cervix | CC | 2.31e-07 | 8.86e-01 | 0.528 |
57614 | RELCH | CCI_2 | Human | Cervix | CC | 2.00e-05 | 1.12e+00 | 0.5249 |
57614 | RELCH | CCI_3 | Human | Cervix | CC | 2.08e-04 | 6.54e-01 | 0.516 |
57614 | RELCH | Tumor | Human | Cervix | CC | 8.11e-04 | -1.24e-01 | 0.1241 |
57614 | RELCH | T3 | Human | Cervix | CC | 1.54e-03 | 1.57e-01 | 0.1389 |
57614 | RELCH | HTA11_2487_2000001011 | Human | Colorectum | SER | 2.44e-05 | 1.98e-01 | -0.1808 |
57614 | RELCH | HTA11_1938_2000001011 | Human | Colorectum | AD | 2.86e-06 | 2.32e-01 | -0.0811 |
57614 | RELCH | HTA11_78_2000001011 | Human | Colorectum | AD | 1.18e-19 | 5.45e-01 | -0.1088 |
57614 | RELCH | HTA11_347_2000001011 | Human | Colorectum | AD | 3.98e-31 | 5.33e-01 | -0.1954 |
57614 | RELCH | HTA11_411_2000001011 | Human | Colorectum | SER | 5.61e-03 | 2.55e-01 | -0.2602 |
57614 | RELCH | HTA11_83_2000001011 | Human | Colorectum | SER | 1.47e-06 | 2.71e-01 | -0.1526 |
57614 | RELCH | HTA11_696_2000001011 | Human | Colorectum | AD | 9.56e-07 | 1.47e-01 | -0.1464 |
57614 | RELCH | HTA11_866_2000001011 | Human | Colorectum | AD | 1.86e-11 | 2.52e-01 | -0.1001 |
57614 | RELCH | HTA11_1391_2000001011 | Human | Colorectum | AD | 4.60e-11 | 2.74e-01 | -0.059 |
57614 | RELCH | HTA11_2992_2000001011 | Human | Colorectum | SER | 1.51e-04 | 2.39e-01 | -0.1706 |
57614 | RELCH | HTA11_5216_2000001011 | Human | Colorectum | SER | 3.03e-06 | 3.36e-01 | -0.1462 |
57614 | RELCH | HTA11_546_2000001011 | Human | Colorectum | AD | 2.76e-07 | 2.90e-01 | -0.0842 |
57614 | RELCH | HTA11_7862_2000001011 | Human | Colorectum | AD | 7.36e-06 | 2.70e-01 | -0.0179 |
57614 | RELCH | HTA11_866_3004761011 | Human | Colorectum | AD | 6.26e-04 | 1.48e-01 | 0.096 |
57614 | RELCH | HTA11_4255_2000001011 | Human | Colorectum | SER | 9.34e-47 | 2.35e+00 | 0.0446 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:0010876 | Colorectum | AD | lipid localization | 120/3918 | 448/18723 | 1.59e-03 | 1.33e-02 | 120 |
GO:0006869 | Colorectum | AD | lipid transport | 108/3918 | 398/18723 | 1.67e-03 | 1.39e-02 | 108 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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