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Gene: PNLIPRP1 |
Gene summary for PNLIPRP1 |
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Gene information | Species | Human | Gene symbol | PNLIPRP1 | Gene ID | 5407 |
Gene name | pancreatic lipase related protein 1 | |
Gene Alias | PLRP1 | |
Cytomap | 10q25.3 | |
Gene Type | protein-coding | GO ID | GO:0006629 | UniProtAcc | P54315 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
5407 | PNLIPRP1 | HTA12-15-2 | Human | Pancreas | PDAC | 3.86e-28 | -1.85e+00 | 0.2315 |
5407 | PNLIPRP1 | HTA12-23-1 | Human | Pancreas | PDAC | 1.35e-18 | -1.85e+00 | 0.3405 |
5407 | PNLIPRP1 | HTA12-25-1 | Human | Pancreas | PDAC | 1.56e-27 | -1.85e+00 | 0.313 |
5407 | PNLIPRP1 | HTA12-26-1 | Human | Pancreas | PDAC | 5.26e-34 | -1.85e+00 | 0.3728 |
5407 | PNLIPRP1 | HTA12-29-1 | Human | Pancreas | PDAC | 1.65e-87 | -1.85e+00 | 0.3722 |
5407 | PNLIPRP1 | HTA12-3-16 | Human | Pancreas | PDAC | 8.17e-05 | -1.85e+00 | 0.1553 |
5407 | PNLIPRP1 | HTA12-30-1 | Human | Pancreas | PDAC | 1.34e-05 | -1.85e+00 | 0.3671 |
5407 | PNLIPRP1 | HTA12-32-1 | Human | Pancreas | PDAC | 3.44e-06 | -1.66e+00 | 0.3624 |
5407 | PNLIPRP1 | HTA12-9-1 | Human | Pancreas | PDAC | 7.00e-45 | -1.81e+00 | 0.1532 |
5407 | PNLIPRP1 | HTA12-9-2 | Human | Pancreas | PDAC | 1.83e-13 | -7.82e-01 | 0.0835 |
5407 | PNLIPRP1 | HTA12-9-3 | Human | Pancreas | PDAC | 1.56e-22 | -1.85e+00 | 0.2045 |
5407 | PNLIPRP1 | 3829-EC | Human | Pancreas | PanIN | 1.20e-04 | 1.40e-01 | 0.009 |
5407 | PNLIPRP1 | 4347-EC | Human | Pancreas | PanIN | 1.52e-27 | -6.19e-01 | 0.0572 |
5407 | PNLIPRP1 | 4741-EC1 | Human | Pancreas | PanIN | 5.42e-38 | 4.65e-01 | 0.0223 |
5407 | PNLIPRP1 | 4741-EC2 | Human | Pancreas | PanIN | 2.57e-36 | 3.69e-01 | 0.0194 |
5407 | PNLIPRP1 | 181429 | Human | Pancreas | PDAC | 6.81e-11 | -1.85e+00 | 0.1416 |
5407 | PNLIPRP1 | 61354830 | Human | Pancreas | PDAC | 1.34e-05 | -1.85e+00 | 0.1458 |
5407 | PNLIPRP1 | DS20191261Tumor | Human | Pancreas | PDAC | 2.56e-56 | -1.85e+00 | 0.1367 |
5407 | PNLIPRP1 | DS20191261TumorKeller | Human | Pancreas | PDAC | 1.77e-14 | -1.85e+00 | 0.1407 |
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Tissue | Expression Dynamics | Abbreviation |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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