GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00017017 | Breast | Precancer | in utero embryonic development | 35/1080 | 367/18723 | 2.47e-03 | 2.27e-02 | 35 |
GO:000170113 | Breast | IDC | in utero embryonic development | 42/1434 | 367/18723 | 5.85e-03 | 4.24e-02 | 42 |
GO:000170122 | Breast | DCIS | in utero embryonic development | 41/1390 | 367/18723 | 5.74e-03 | 4.13e-02 | 41 |
GO:20007362 | Cervix | CC | regulation of stem cell differentiation | 19/2311 | 58/18723 | 4.01e-05 | 6.21e-04 | 19 |
GO:00488634 | Cervix | CC | stem cell differentiation | 46/2311 | 206/18723 | 4.11e-05 | 6.36e-04 | 46 |
GO:00017018 | Cervix | CC | in utero embryonic development | 71/2311 | 367/18723 | 7.21e-05 | 1.00e-03 | 71 |
GO:20007372 | Cervix | CC | negative regulation of stem cell differentiation | 10/2311 | 23/18723 | 2.00e-04 | 2.29e-03 | 10 |
GO:00022443 | Cervix | CC | hematopoietic progenitor cell differentiation | 26/2311 | 114/18723 | 1.30e-03 | 1.03e-02 | 26 |
GO:0060218 | Cervix | CC | hematopoietic stem cell differentiation | 10/2311 | 30/18723 | 2.33e-03 | 1.66e-02 | 10 |
GO:1901532 | Cervix | CC | regulation of hematopoietic progenitor cell differentiation | 10/2311 | 32/18723 | 3.96e-03 | 2.48e-02 | 10 |
GO:1902036 | Cervix | CC | regulation of hematopoietic stem cell differentiation | 6/2311 | 14/18723 | 4.36e-03 | 2.67e-02 | 6 |
GO:004886313 | Cervix | N_HPV | stem cell differentiation | 14/534 | 206/18723 | 2.43e-03 | 2.20e-02 | 14 |
GO:200073711 | Cervix | N_HPV | negative regulation of stem cell differentiation | 4/534 | 23/18723 | 3.76e-03 | 3.00e-02 | 4 |
GO:200073611 | Cervix | N_HPV | regulation of stem cell differentiation | 6/534 | 58/18723 | 6.04e-03 | 4.17e-02 | 6 |
GO:0001701 | Colorectum | AD | in utero embryonic development | 110/3918 | 367/18723 | 2.36e-05 | 4.62e-04 | 110 |
GO:00017012 | Colorectum | MSS | in utero embryonic development | 99/3467 | 367/18723 | 3.71e-05 | 7.10e-04 | 99 |
GO:0002244 | Colorectum | MSS | hematopoietic progenitor cell differentiation | 32/3467 | 114/18723 | 8.07e-03 | 4.91e-02 | 32 |
GO:00017013 | Colorectum | FAP | in utero embryonic development | 81/2622 | 367/18723 | 1.58e-05 | 4.10e-04 | 81 |
GO:00022441 | Colorectum | FAP | hematopoietic progenitor cell differentiation | 29/2622 | 114/18723 | 8.35e-04 | 8.71e-03 | 29 |
GO:0048863 | Colorectum | FAP | stem cell differentiation | 44/2622 | 206/18723 | 2.48e-03 | 1.96e-02 | 44 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
N4BP2 | SNV | Missense_Mutation | | c.4384N>G | p.Gln1462Glu | p.Q1462E | Q86UW6 | protein_coding | deleterious(0.03) | benign(0.03) | TCGA-A2-A0EY-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | SD |
N4BP2 | SNV | Missense_Mutation | rs201204950 | c.4933C>T | p.Arg1645Trp | p.R1645W | Q86UW6 | protein_coding | deleterious(0) | probably_damaging(0.916) | TCGA-AN-A046-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
N4BP2 | SNV | Missense_Mutation | | c.935N>T | p.Thr312Ile | p.T312I | Q86UW6 | protein_coding | tolerated(0.33) | benign(0.001) | TCGA-AN-A0FZ-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
N4BP2 | SNV | Missense_Mutation | | c.4277C>T | p.Ser1426Phe | p.S1426F | Q86UW6 | protein_coding | deleterious(0) | probably_damaging(0.994) | TCGA-AR-A0TX-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
N4BP2 | SNV | Missense_Mutation | | c.4859N>T | p.Asp1620Val | p.D1620V | Q86UW6 | protein_coding | deleterious(0) | probably_damaging(0.952) | TCGA-BH-A203-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
N4BP2 | SNV | Missense_Mutation | | c.2320N>C | p.Ser774Pro | p.S774P | Q86UW6 | protein_coding | deleterious(0.03) | benign(0.023) | TCGA-C8-A1HK-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
N4BP2 | SNV | Missense_Mutation | | c.3085N>C | p.Glu1029Gln | p.E1029Q | Q86UW6 | protein_coding | deleterious(0) | probably_damaging(0.968) | TCGA-C8-A8HQ-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
N4BP2 | SNV | Missense_Mutation | | c.2156N>A | p.Ser719Tyr | p.S719Y | Q86UW6 | protein_coding | tolerated(0.12) | benign(0.086) | TCGA-D8-A1JG-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | doxorubicin | SD |
N4BP2 | SNV | Missense_Mutation | | c.1880N>C | p.Leu627Ser | p.L627S | Q86UW6 | protein_coding | tolerated(0.16) | benign(0) | TCGA-D8-A1XK-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | doxorubicine+cyclophosphamide | SD |
N4BP2 | SNV | Missense_Mutation | novel | c.70G>A | p.Val24Ile | p.V24I | Q86UW6 | protein_coding | deleterious(0.01) | benign(0.041) | TCGA-2W-A8YY-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | CR |