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Gene: MRPS30-DT |
Gene summary for MRPS30-DT |
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Gene information | Species | Human | Gene symbol | MRPS30-DT | Gene ID | 100506674 |
Gene name | MRPS30 divergent transcript | |
Gene Alias | BRCAT54 | |
Cytomap | 5p12 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100506674 | MRPS30-DT | GSM4909297 | Human | Breast | IDC | 2.28e-03 | 2.45e-01 | 0.1517 |
100506674 | MRPS30-DT | GSM4909301 | Human | Breast | IDC | 2.35e-69 | 1.21e+00 | 0.1577 |
100506674 | MRPS30-DT | GSM4909302 | Human | Breast | IDC | 1.64e-05 | 3.09e-01 | 0.1545 |
100506674 | MRPS30-DT | GSM4909306 | Human | Breast | IDC | 6.10e-53 | 9.65e-01 | 0.1564 |
100506674 | MRPS30-DT | GSM4909307 | Human | Breast | IDC | 9.67e-87 | 1.38e+00 | 0.1569 |
100506674 | MRPS30-DT | GSM4909308 | Human | Breast | IDC | 5.43e-123 | 1.64e+00 | 0.158 |
100506674 | MRPS30-DT | GSM4909309 | Human | Breast | IDC | 4.66e-09 | 4.47e-01 | 0.0483 |
100506674 | MRPS30-DT | GSM4909321 | Human | Breast | IDC | 8.11e-03 | 2.23e-01 | 0.1559 |
100506674 | MRPS30-DT | M5 | Human | Breast | IDC | 3.68e-14 | 9.22e-01 | 0.1598 |
100506674 | MRPS30-DT | NCCBC3 | Human | Breast | DCIS | 4.16e-07 | 4.13e-01 | 0.1198 |
100506674 | MRPS30-DT | P3 | Human | Breast | IDC | 2.82e-17 | 9.97e-01 | 0.1542 |
100506674 | MRPS30-DT | PTC07 | Human | Thyroid | PTC | 1.09e-02 | 7.97e-02 | 0.2044 |
100506674 | MRPS30-DT | ATC13 | Human | Thyroid | ATC | 4.54e-53 | 9.58e-01 | 0.34 |
100506674 | MRPS30-DT | ATC5 | Human | Thyroid | ATC | 3.84e-65 | 1.02e+00 | 0.34 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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