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Gene: MIAT |
Gene summary for MIAT |
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Gene information | Species | Human | Gene symbol | MIAT | Gene ID | 440823 |
Gene name | myocardial infarction associated transcript | |
Gene Alias | C22orf35 | |
Cytomap | 22q12.1 | |
Gene Type | ncRNA | GO ID | GO:0001708 | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
440823 | MIAT | LZE7T | Human | Esophagus | ESCC | 1.56e-14 | 9.01e-01 | 0.0667 |
440823 | MIAT | P4T-E | Human | Esophagus | ESCC | 1.36e-04 | 1.41e-01 | 0.1323 |
440823 | MIAT | P26T-E | Human | Esophagus | ESCC | 3.50e-02 | 1.31e-01 | 0.1276 |
440823 | MIAT | P28T-E | Human | Esophagus | ESCC | 2.39e-24 | 9.72e-01 | 0.1149 |
440823 | MIAT | P30T-E | Human | Esophagus | ESCC | 6.12e-09 | 4.59e-01 | 0.137 |
440823 | MIAT | P52T-E | Human | Esophagus | ESCC | 1.78e-03 | 1.31e-01 | 0.1555 |
440823 | MIAT | P62T-E | Human | Esophagus | ESCC | 1.20e-02 | 8.52e-02 | 0.1302 |
440823 | MIAT | P107T-E | Human | Esophagus | ESCC | 3.51e-03 | 1.08e-01 | 0.171 |
440823 | MIAT | P130T-E | Human | Esophagus | ESCC | 1.66e-02 | 8.66e-02 | 0.1676 |
440823 | MIAT | male-WTA | Human | Thyroid | PTC | 3.77e-04 | 6.64e-02 | 0.1037 |
440823 | MIAT | PTC06 | Human | Thyroid | PTC | 5.78e-05 | 2.44e-01 | 0.2057 |
440823 | MIAT | ATC09 | Human | Thyroid | ATC | 2.95e-02 | 1.68e-01 | 0.2871 |
440823 | MIAT | ATC11 | Human | Thyroid | ATC | 3.71e-05 | 9.93e-01 | 0.3386 |
440823 | MIAT | ATC2 | Human | Thyroid | ATC | 3.34e-11 | 1.10e+00 | 0.34 |
440823 | MIAT | ATC3 | Human | Thyroid | ATC | 5.52e-09 | 9.26e-01 | 0.338 |
440823 | MIAT | ATC4 | Human | Thyroid | ATC | 2.74e-03 | 1.13e-01 | 0.34 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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