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Gene: MAPKAPK5-AS1 |
Gene summary for MAPKAPK5-AS1 |
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Gene information | Species | Human | Gene symbol | MAPKAPK5-AS1 | Gene ID | 51275 |
Gene name | MAPKAPK5 antisense RNA 1 | |
Gene Alias | C12orf47 | |
Cytomap | 12q24.12 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
51275 | MAPKAPK5-AS1 | LZE4T | Human | Esophagus | ESCC | 1.89e-10 | 3.68e-01 | 0.0811 |
51275 | MAPKAPK5-AS1 | LZE5T | Human | Esophagus | ESCC | 4.17e-03 | 1.79e-01 | 0.0514 |
51275 | MAPKAPK5-AS1 | LZE7T | Human | Esophagus | ESCC | 1.95e-08 | 4.77e-01 | 0.0667 |
51275 | MAPKAPK5-AS1 | LZE8T | Human | Esophagus | ESCC | 6.84e-03 | 2.03e-01 | 0.067 |
51275 | MAPKAPK5-AS1 | LZE22T | Human | Esophagus | ESCC | 2.00e-04 | 3.68e-01 | 0.068 |
51275 | MAPKAPK5-AS1 | LZE24T | Human | Esophagus | ESCC | 1.31e-20 | 5.81e-01 | 0.0596 |
51275 | MAPKAPK5-AS1 | LZE21T | Human | Esophagus | ESCC | 1.36e-06 | 2.71e-01 | 0.0655 |
51275 | MAPKAPK5-AS1 | LZE6T | Human | Esophagus | ESCC | 5.10e-08 | 2.23e-01 | 0.0845 |
51275 | MAPKAPK5-AS1 | P1T-E | Human | Esophagus | ESCC | 2.03e-08 | 6.38e-01 | 0.0875 |
51275 | MAPKAPK5-AS1 | P2T-E | Human | Esophagus | ESCC | 1.22e-37 | 6.68e-01 | 0.1177 |
51275 | MAPKAPK5-AS1 | P4T-E | Human | Esophagus | ESCC | 7.62e-24 | 5.81e-01 | 0.1323 |
51275 | MAPKAPK5-AS1 | P5T-E | Human | Esophagus | ESCC | 9.98e-15 | 3.71e-01 | 0.1327 |
51275 | MAPKAPK5-AS1 | P8T-E | Human | Esophagus | ESCC | 3.70e-27 | 5.27e-01 | 0.0889 |
51275 | MAPKAPK5-AS1 | P9T-E | Human | Esophagus | ESCC | 9.45e-12 | 3.12e-01 | 0.1131 |
51275 | MAPKAPK5-AS1 | P10T-E | Human | Esophagus | ESCC | 1.97e-38 | 6.28e-01 | 0.116 |
51275 | MAPKAPK5-AS1 | P11T-E | Human | Esophagus | ESCC | 5.10e-15 | 5.90e-01 | 0.1426 |
51275 | MAPKAPK5-AS1 | P12T-E | Human | Esophagus | ESCC | 1.18e-26 | 4.44e-01 | 0.1122 |
51275 | MAPKAPK5-AS1 | P15T-E | Human | Esophagus | ESCC | 4.69e-20 | 4.53e-01 | 0.1149 |
51275 | MAPKAPK5-AS1 | P16T-E | Human | Esophagus | ESCC | 1.20e-26 | 5.03e-01 | 0.1153 |
51275 | MAPKAPK5-AS1 | P17T-E | Human | Esophagus | ESCC | 1.06e-05 | 4.10e-01 | 0.1278 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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