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Gene: LINC01725 |
Gene summary for LINC01725 |
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Gene information | Species | Human | Gene symbol | LINC01725 | Gene ID | 101927587 |
Gene name | long intergenic non-protein coding RNA 1725 | |
Gene Alias | LINC01725 | |
Cytomap | 1p31.1 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
101927587 | LINC01725 | NAFLD1 | Human | Liver | NAFLD | 3.11e-17 | 1.22e+00 | -0.04 |
101927587 | LINC01725 | S41 | Human | Liver | Cirrhotic | 1.75e-03 | 6.40e-01 | -0.0343 |
101927587 | LINC01725 | HCC1_Meng | Human | Liver | HCC | 4.93e-06 | -1.85e-01 | 0.0246 |
101927587 | LINC01725 | HCC2_Meng | Human | Liver | HCC | 1.02e-04 | -1.85e-01 | 0.0107 |
101927587 | LINC01725 | cirrhotic1 | Human | Liver | Cirrhotic | 1.05e-05 | -1.85e-01 | 0.0202 |
101927587 | LINC01725 | cirrhotic2 | Human | Liver | Cirrhotic | 1.05e-05 | -1.85e-01 | 0.0201 |
101927587 | LINC01725 | cirrhotic3 | Human | Liver | Cirrhotic | 2.78e-03 | -1.85e-01 | 0.0215 |
101927587 | LINC01725 | Pt13.a | Human | Liver | HCC | 4.93e-06 | -1.85e-01 | 0.021 |
101927587 | LINC01725 | Pt13.b | Human | Liver | HCC | 1.85e-02 | -1.85e-01 | 0.0251 |
101927587 | LINC01725 | Pt14.d | Human | Liver | HCC | 4.93e-06 | -1.85e-01 | 0.0143 |
101927587 | LINC01725 | S016 | Human | Liver | HCC | 1.56e-02 | -1.85e-01 | 0.2243 |
101927587 | LINC01725 | HTA12-25-1 | Human | Pancreas | PDAC | 3.20e-04 | 5.34e-01 | 0.313 |
101927587 | LINC01725 | HTA12-26-1 | Human | Pancreas | PDAC | 1.18e-05 | 3.69e-01 | 0.3728 |
101927587 | LINC01725 | HTA12-29-1 | Human | Pancreas | PDAC | 5.37e-27 | 7.48e-01 | 0.3722 |
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Tissue | Expression Dynamics | Abbreviation |
Liver | ![]() | HCC: Hepatocellular carcinoma |
NAFLD: Non-alcoholic fatty liver disease |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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