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Gene: LINC01137 |
Gene summary for LINC01137 |
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Gene information | Species | Human | Gene symbol | LINC01137 | Gene ID | 728431 |
Gene name | ZC3H12A divergent transcript | |
Gene Alias | LINC01137 | |
Cytomap | 1p34.3 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
728431 | LINC01137 | C04 | Human | Oral cavity | OSCC | 3.25e-08 | 2.53e-01 | 0.2633 |
728431 | LINC01137 | C21 | Human | Oral cavity | OSCC | 4.19e-11 | 2.52e-01 | 0.2678 |
728431 | LINC01137 | C30 | Human | Oral cavity | OSCC | 1.04e-22 | 6.75e-01 | 0.3055 |
728431 | LINC01137 | C43 | Human | Oral cavity | OSCC | 3.61e-02 | 8.89e-02 | 0.1704 |
728431 | LINC01137 | C06 | Human | Oral cavity | OSCC | 6.22e-04 | 5.72e-01 | 0.2699 |
728431 | LINC01137 | LP15 | Human | Oral cavity | LP | 9.93e-03 | 6.39e-01 | 0.2174 |
728431 | LINC01137 | LP17 | Human | Oral cavity | LP | 3.06e-04 | 2.90e-01 | 0.2349 |
728431 | LINC01137 | SYSMH1 | Human | Oral cavity | OSCC | 2.37e-06 | 1.44e-01 | 0.1127 |
728431 | LINC01137 | SYSMH2 | Human | Oral cavity | OSCC | 6.92e-03 | 1.45e-01 | 0.2326 |
728431 | LINC01137 | SYSMH3 | Human | Oral cavity | OSCC | 1.17e-05 | 1.76e-01 | 0.2442 |
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Tissue | Expression Dynamics | Abbreviation |
Oral Cavity | ![]() | EOLP: Erosive Oral lichen planus |
LP: leukoplakia | ||
NEOLP: Non-erosive oral lichen planus | ||
OSCC: Oral squamous cell carcinoma |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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