![]() |
|||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: LINC00863 |
Gene summary for LINC00863 |
![]() |
Gene information | Species | Human | Gene symbol | LINC00863 | Gene ID | 439994 |
Gene name | long intergenic non-protein coding RNA 863 | |
Gene Alias | LINC00863 | |
Cytomap | 10q23.2 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
Top |
Malignant transformation analysis |
![]() |
![]() |
Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
439994 | LINC00863 | LZE4T | Human | Esophagus | ESCC | 6.30e-06 | 2.90e-01 | 0.0811 |
439994 | LINC00863 | LZE22D1 | Human | Esophagus | HGIN | 4.98e-02 | 2.29e-01 | 0.0595 |
439994 | LINC00863 | LZE22T | Human | Esophagus | ESCC | 1.14e-02 | 3.54e-01 | 0.068 |
439994 | LINC00863 | LZE24T | Human | Esophagus | ESCC | 8.69e-12 | 3.40e-01 | 0.0596 |
439994 | LINC00863 | LZE21T | Human | Esophagus | ESCC | 8.87e-03 | 3.78e-01 | 0.0655 |
439994 | LINC00863 | P1T-E | Human | Esophagus | ESCC | 4.54e-09 | 5.91e-01 | 0.0875 |
439994 | LINC00863 | P2T-E | Human | Esophagus | ESCC | 2.56e-16 | 3.19e-01 | 0.1177 |
439994 | LINC00863 | P4T-E | Human | Esophagus | ESCC | 2.98e-18 | 4.88e-01 | 0.1323 |
439994 | LINC00863 | P5T-E | Human | Esophagus | ESCC | 1.85e-18 | 4.76e-01 | 0.1327 |
439994 | LINC00863 | P8T-E | Human | Esophagus | ESCC | 8.08e-19 | 3.33e-01 | 0.0889 |
439994 | LINC00863 | P9T-E | Human | Esophagus | ESCC | 5.23e-15 | 2.99e-01 | 0.1131 |
439994 | LINC00863 | P10T-E | Human | Esophagus | ESCC | 2.86e-20 | 3.70e-01 | 0.116 |
439994 | LINC00863 | P11T-E | Human | Esophagus | ESCC | 8.67e-10 | 3.80e-01 | 0.1426 |
439994 | LINC00863 | P12T-E | Human | Esophagus | ESCC | 3.22e-45 | 8.48e-01 | 0.1122 |
439994 | LINC00863 | P15T-E | Human | Esophagus | ESCC | 4.39e-12 | 3.07e-01 | 0.1149 |
439994 | LINC00863 | P16T-E | Human | Esophagus | ESCC | 4.09e-46 | 7.67e-01 | 0.1153 |
439994 | LINC00863 | P20T-E | Human | Esophagus | ESCC | 4.68e-17 | 4.74e-01 | 0.1124 |
439994 | LINC00863 | P21T-E | Human | Esophagus | ESCC | 4.17e-05 | 1.64e-01 | 0.1617 |
439994 | LINC00863 | P22T-E | Human | Esophagus | ESCC | 1.51e-34 | 6.84e-01 | 0.1236 |
439994 | LINC00863 | P23T-E | Human | Esophagus | ESCC | 2.41e-11 | 2.61e-01 | 0.108 |
Page: 1 2 3 |
![]() |
Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
Top |
Malignant transformation related pathway analysis |
![]() |
![]() |
Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
![]() |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
![]() |
Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
Top |
Cell-cell communication analysis |
![]() |
Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
Top |
Single-cell gene regulatory network inference analysis |
![]() |
TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
Top |
Somatic mutation of malignant transformation related genes |
![]() |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
Top |
Related drugs of malignant transformation related genes |
![]() |
(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |