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Gene: LINC00685 |
Gene summary for LINC00685 |
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Gene information | Species | Human | Gene symbol | LINC00685 | Gene ID | 283981 |
Gene name | long intergenic non-protein coding RNA 685 | |
Gene Alias | CXYorf10 | |
Cytomap | X | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
283981 | LINC00685 | HTA11_10623_2000001011 | Human | Colorectum | AD | 7.19e-04 | 7.86e-01 | -0.0177 |
283981 | LINC00685 | HTA11_7696_3000711011 | Human | Colorectum | AD | 3.62e-03 | 2.86e-01 | 0.0674 |
283981 | LINC00685 | HTA11_99999965104_69814 | Human | Colorectum | MSS | 3.30e-07 | 7.78e-01 | 0.281 |
283981 | LINC00685 | HTA11_99999974143_84620 | Human | Colorectum | MSS | 3.65e-05 | 3.88e-01 | 0.3005 |
283981 | LINC00685 | A002-C-201 | Human | Colorectum | FAP | 1.23e-05 | -1.63e-01 | 0.0324 |
283981 | LINC00685 | A001-C-119 | Human | Colorectum | FAP | 5.17e-05 | -2.03e-01 | -0.1557 |
283981 | LINC00685 | A002-C-205 | Human | Colorectum | FAP | 5.48e-07 | -1.92e-01 | -0.1236 |
283981 | LINC00685 | A014-C-108 | Human | Colorectum | FAP | 9.16e-03 | -1.83e-01 | -0.124 |
283981 | LINC00685 | A015-C-006 | Human | Colorectum | FAP | 1.46e-02 | -1.36e-01 | -0.0994 |
283981 | LINC00685 | A002-C-114 | Human | Colorectum | FAP | 2.46e-04 | -1.72e-01 | -0.1561 |
283981 | LINC00685 | A015-C-104 | Human | Colorectum | FAP | 3.05e-02 | -1.60e-01 | -0.1899 |
283981 | LINC00685 | A002-C-016 | Human | Colorectum | FAP | 8.86e-03 | -1.30e-01 | 0.0521 |
283981 | LINC00685 | A002-C-116 | Human | Colorectum | FAP | 4.38e-06 | -1.92e-01 | -0.0452 |
283981 | LINC00685 | A014-C-008 | Human | Colorectum | FAP | 3.90e-02 | -1.64e-01 | -0.191 |
283981 | LINC00685 | A018-E-020 | Human | Colorectum | FAP | 2.46e-08 | -2.03e-01 | -0.2034 |
283981 | LINC00685 | CRC-3-11773 | Human | Colorectum | CRC | 1.61e-03 | -1.81e-01 | 0.2564 |
283981 | LINC00685 | C30 | Human | Oral cavity | OSCC | 2.20e-09 | 4.33e-01 | 0.3055 |
283981 | LINC00685 | C38 | Human | Oral cavity | OSCC | 5.26e-05 | 6.56e-01 | 0.172 |
283981 | LINC00685 | C46 | Human | Oral cavity | OSCC | 4.12e-05 | 1.95e-01 | 0.1673 |
283981 | LINC00685 | C57 | Human | Oral cavity | OSCC | 3.01e-09 | 3.77e-01 | 0.1679 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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