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Gene: LINC00680 |
Gene summary for LINC00680 |
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Gene information | Species | Human | Gene symbol | LINC00680 | Gene ID | 106660612 |
Gene name | long intergenic non-protein coding RNA 680 | |
Gene Alias | LINC00680 | |
Cytomap | 6p11.2 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
106660612 | LINC00680 | P1T-E | Human | Esophagus | ESCC | 1.45e-10 | 3.33e-01 | 0.0875 |
106660612 | LINC00680 | P2T-E | Human | Esophagus | ESCC | 5.81e-16 | 1.66e-01 | 0.1177 |
106660612 | LINC00680 | P4T-E | Human | Esophagus | ESCC | 1.45e-20 | 3.95e-01 | 0.1323 |
106660612 | LINC00680 | P5T-E | Human | Esophagus | ESCC | 2.93e-05 | 9.87e-02 | 0.1327 |
106660612 | LINC00680 | P8T-E | Human | Esophagus | ESCC | 3.66e-02 | 9.57e-02 | 0.0889 |
106660612 | LINC00680 | P9T-E | Human | Esophagus | ESCC | 6.74e-06 | 1.48e-01 | 0.1131 |
106660612 | LINC00680 | P10T-E | Human | Esophagus | ESCC | 2.91e-19 | 3.83e-01 | 0.116 |
106660612 | LINC00680 | P12T-E | Human | Esophagus | ESCC | 2.29e-15 | 2.94e-01 | 0.1122 |
106660612 | LINC00680 | P15T-E | Human | Esophagus | ESCC | 7.99e-08 | 1.66e-01 | 0.1149 |
106660612 | LINC00680 | P16T-E | Human | Esophagus | ESCC | 2.11e-17 | 2.38e-01 | 0.1153 |
106660612 | LINC00680 | P17T-E | Human | Esophagus | ESCC | 8.50e-05 | 1.75e-01 | 0.1278 |
106660612 | LINC00680 | P20T-E | Human | Esophagus | ESCC | 1.17e-04 | 1.19e-01 | 0.1124 |
106660612 | LINC00680 | P21T-E | Human | Esophagus | ESCC | 1.12e-07 | 8.85e-02 | 0.1617 |
106660612 | LINC00680 | P22T-E | Human | Esophagus | ESCC | 4.02e-10 | 2.15e-01 | 0.1236 |
106660612 | LINC00680 | P23T-E | Human | Esophagus | ESCC | 1.14e-03 | 1.04e-01 | 0.108 |
106660612 | LINC00680 | P26T-E | Human | Esophagus | ESCC | 3.37e-08 | 1.55e-01 | 0.1276 |
106660612 | LINC00680 | P27T-E | Human | Esophagus | ESCC | 2.02e-20 | 4.45e-01 | 0.1055 |
106660612 | LINC00680 | P28T-E | Human | Esophagus | ESCC | 1.79e-11 | 1.90e-01 | 0.1149 |
106660612 | LINC00680 | P30T-E | Human | Esophagus | ESCC | 1.56e-18 | 8.81e-01 | 0.137 |
106660612 | LINC00680 | P31T-E | Human | Esophagus | ESCC | 9.12e-08 | 1.30e-01 | 0.1251 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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