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Gene: LINC00519 |
Gene summary for LINC00519 |
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Gene information | Species | Human | Gene symbol | LINC00519 | Gene ID | 161342 |
Gene name | long intergenic non-protein coding RNA 519 | |
Gene Alias | C14orf30 | |
Cytomap | 14q22.1 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
161342 | LINC00519 | LZE4T | Human | Esophagus | ESCC | 1.39e-20 | 6.00e-01 | 0.0811 |
161342 | LINC00519 | LZE20T | Human | Esophagus | ESCC | 1.97e-04 | 1.53e-01 | 0.0662 |
161342 | LINC00519 | P4T-E | Human | Esophagus | ESCC | 3.78e-04 | 1.57e-01 | 0.1323 |
161342 | LINC00519 | P9T-E | Human | Esophagus | ESCC | 4.53e-16 | 3.73e-01 | 0.1131 |
161342 | LINC00519 | P10T-E | Human | Esophagus | ESCC | 4.31e-06 | 1.56e-01 | 0.116 |
161342 | LINC00519 | P11T-E | Human | Esophagus | ESCC | 2.46e-02 | 2.37e-01 | 0.1426 |
161342 | LINC00519 | P12T-E | Human | Esophagus | ESCC | 8.40e-04 | 1.06e-01 | 0.1122 |
161342 | LINC00519 | P15T-E | Human | Esophagus | ESCC | 5.62e-30 | 7.02e-01 | 0.1149 |
161342 | LINC00519 | P22T-E | Human | Esophagus | ESCC | 8.56e-12 | 2.22e-01 | 0.1236 |
161342 | LINC00519 | P23T-E | Human | Esophagus | ESCC | 1.14e-03 | 1.34e-01 | 0.108 |
161342 | LINC00519 | P26T-E | Human | Esophagus | ESCC | 4.24e-18 | 2.89e-01 | 0.1276 |
161342 | LINC00519 | P27T-E | Human | Esophagus | ESCC | 1.76e-12 | 2.68e-01 | 0.1055 |
161342 | LINC00519 | P28T-E | Human | Esophagus | ESCC | 4.40e-09 | 2.20e-01 | 0.1149 |
161342 | LINC00519 | P30T-E | Human | Esophagus | ESCC | 7.15e-21 | 6.31e-01 | 0.137 |
161342 | LINC00519 | P37T-E | Human | Esophagus | ESCC | 2.57e-08 | 2.18e-01 | 0.1371 |
161342 | LINC00519 | P42T-E | Human | Esophagus | ESCC | 2.93e-13 | 4.08e-01 | 0.1175 |
161342 | LINC00519 | P47T-E | Human | Esophagus | ESCC | 9.56e-08 | 1.79e-01 | 0.1067 |
161342 | LINC00519 | P49T-E | Human | Esophagus | ESCC | 1.17e-11 | 7.91e-01 | 0.1768 |
161342 | LINC00519 | P52T-E | Human | Esophagus | ESCC | 8.84e-05 | 1.38e-01 | 0.1555 |
161342 | LINC00519 | P61T-E | Human | Esophagus | ESCC | 1.62e-06 | 2.01e-01 | 0.099 |
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Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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