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Gene: KIAA0196 |
Gene summary for KIAA0196 |
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Gene information | Species | Human | Gene symbol | KIAA0196 | Gene ID | 9897 |
Gene name | WASH complex subunit 5 | |
Gene Alias | KIAA0196 | |
Cytomap | 8q24.13 | |
Gene Type | protein-coding | GO ID | GO:0000003 | UniProtAcc | E7EQI7 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
9897 | KIAA0196 | HTA11_99999970781_79442 | Human | Colorectum | MSS | 8.56e-30 | 4.72e-01 | 0.294 |
9897 | KIAA0196 | HTA11_99999965062_69753 | Human | Colorectum | MSI-H | 3.42e-04 | 5.36e-01 | 0.3487 |
9897 | KIAA0196 | HTA11_99999965104_69814 | Human | Colorectum | MSS | 3.54e-19 | 6.06e-01 | 0.281 |
9897 | KIAA0196 | HTA11_99999971662_82457 | Human | Colorectum | MSS | 1.29e-28 | 5.34e-01 | 0.3859 |
9897 | KIAA0196 | HTA11_99999974143_84620 | Human | Colorectum | MSS | 3.19e-14 | 2.63e-01 | 0.3005 |
9897 | KIAA0196 | P2T-E | Human | Esophagus | ESCC | 9.49e-16 | 2.37e-01 | 0.1177 |
9897 | KIAA0196 | P4T-E | Human | Esophagus | ESCC | 1.58e-15 | 2.06e-01 | 0.1323 |
9897 | KIAA0196 | P5T-E | Human | Esophagus | ESCC | 3.78e-08 | 1.30e-01 | 0.1327 |
9897 | KIAA0196 | P8T-E | Human | Esophagus | ESCC | 7.99e-12 | 1.87e-01 | 0.0889 |
9897 | KIAA0196 | P9T-E | Human | Esophagus | ESCC | 3.38e-10 | 1.67e-01 | 0.1131 |
9897 | KIAA0196 | P10T-E | Human | Esophagus | ESCC | 7.10e-19 | 1.71e-01 | 0.116 |
9897 | KIAA0196 | P11T-E | Human | Esophagus | ESCC | 1.42e-11 | 3.73e-01 | 0.1426 |
9897 | KIAA0196 | P12T-E | Human | Esophagus | ESCC | 1.93e-19 | 4.16e-01 | 0.1122 |
9897 | KIAA0196 | P15T-E | Human | Esophagus | ESCC | 5.11e-16 | 3.01e-01 | 0.1149 |
9897 | KIAA0196 | P16T-E | Human | Esophagus | ESCC | 3.63e-19 | 3.88e-01 | 0.1153 |
9897 | KIAA0196 | P17T-E | Human | Esophagus | ESCC | 3.00e-06 | 3.07e-01 | 0.1278 |
9897 | KIAA0196 | P19T-E | Human | Esophagus | ESCC | 1.58e-09 | 4.39e-01 | 0.1662 |
9897 | KIAA0196 | P20T-E | Human | Esophagus | ESCC | 1.12e-13 | 2.05e-01 | 0.1124 |
9897 | KIAA0196 | P21T-E | Human | Esophagus | ESCC | 2.57e-26 | 4.35e-01 | 0.1617 |
9897 | KIAA0196 | P22T-E | Human | Esophagus | ESCC | 4.52e-33 | 5.93e-01 | 0.1236 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
hsa0414422 | Liver | HCC | Endocytosis | 178/4020 | 251/8465 | 2.03e-14 | 5.22e-13 | 2.91e-13 | 178 |
hsa0414432 | Liver | HCC | Endocytosis | 178/4020 | 251/8465 | 2.03e-14 | 5.22e-13 | 2.91e-13 | 178 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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