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Gene: JPT1 |
Gene summary for JPT1 |
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Gene information | Species | Human | Gene symbol | JPT1 | Gene ID | 51155 |
Gene name | Jupiter microtubule associated homolog 1 | |
Gene Alias | ARM2 | |
Cytomap | 17q25.1 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | Q9UK76 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
51155 | JPT1 | GSM4909281 | Human | Breast | IDC | 1.43e-25 | 5.78e-01 | 0.21 |
51155 | JPT1 | GSM4909282 | Human | Breast | IDC | 2.93e-17 | 4.62e-01 | -0.0288 |
51155 | JPT1 | GSM4909285 | Human | Breast | IDC | 6.40e-31 | 5.78e-01 | 0.21 |
51155 | JPT1 | GSM4909286 | Human | Breast | IDC | 1.03e-07 | 2.93e-01 | 0.1081 |
51155 | JPT1 | GSM4909287 | Human | Breast | IDC | 4.41e-28 | 7.85e-01 | 0.2057 |
51155 | JPT1 | GSM4909288 | Human | Breast | IDC | 5.30e-03 | 4.73e-01 | 0.0988 |
51155 | JPT1 | GSM4909289 | Human | Breast | IDC | 4.67e-14 | 9.68e-01 | 0.1064 |
51155 | JPT1 | GSM4909290 | Human | Breast | IDC | 8.81e-53 | 1.11e+00 | 0.2096 |
51155 | JPT1 | GSM4909291 | Human | Breast | IDC | 4.07e-06 | 3.88e-01 | 0.1753 |
51155 | JPT1 | GSM4909293 | Human | Breast | IDC | 5.99e-38 | 6.03e-01 | 0.1581 |
51155 | JPT1 | GSM4909294 | Human | Breast | IDC | 2.18e-03 | 2.42e-01 | 0.2022 |
51155 | JPT1 | GSM4909296 | Human | Breast | IDC | 5.05e-04 | 1.82e-01 | 0.1524 |
51155 | JPT1 | GSM4909297 | Human | Breast | IDC | 1.32e-03 | 1.71e-01 | 0.1517 |
51155 | JPT1 | GSM4909302 | Human | Breast | IDC | 1.58e-07 | 3.96e-01 | 0.1545 |
51155 | JPT1 | GSM4909304 | Human | Breast | IDC | 2.71e-30 | 6.37e-01 | 0.1636 |
51155 | JPT1 | GSM4909305 | Human | Breast | IDC | 6.03e-03 | 1.69e-01 | 0.0436 |
51155 | JPT1 | GSM4909307 | Human | Breast | IDC | 8.63e-22 | 5.65e-01 | 0.1569 |
51155 | JPT1 | GSM4909308 | Human | Breast | IDC | 5.03e-21 | 5.54e-01 | 0.158 |
51155 | JPT1 | GSM4909311 | Human | Breast | IDC | 5.18e-09 | -1.39e-01 | 0.1534 |
51155 | JPT1 | GSM4909312 | Human | Breast | IDC | 4.68e-02 | 6.89e-02 | 0.1552 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |