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Gene: INAFM1 |
Gene summary for INAFM1 |
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Gene information | Species | Human | Gene symbol | INAFM1 | Gene ID | 255783 |
Gene name | InaF motif containing 1 | |
Gene Alias | PRR24 | |
Cytomap | 19q13.32 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | C9JVW0 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
255783 | INAFM1 | LZE24T | Human | Esophagus | ESCC | 6.90e-13 | 1.94e-01 | 0.0596 |
255783 | INAFM1 | P1T-E | Human | Esophagus | ESCC | 1.07e-03 | 2.96e-01 | 0.0875 |
255783 | INAFM1 | P2T-E | Human | Esophagus | ESCC | 7.38e-13 | 1.66e-01 | 0.1177 |
255783 | INAFM1 | P4T-E | Human | Esophagus | ESCC | 4.34e-17 | 4.49e-01 | 0.1323 |
255783 | INAFM1 | P5T-E | Human | Esophagus | ESCC | 9.99e-68 | 1.55e+00 | 0.1327 |
255783 | INAFM1 | P8T-E | Human | Esophagus | ESCC | 1.06e-31 | 7.52e-01 | 0.0889 |
255783 | INAFM1 | P9T-E | Human | Esophagus | ESCC | 2.66e-13 | 4.37e-01 | 0.1131 |
255783 | INAFM1 | P10T-E | Human | Esophagus | ESCC | 3.76e-14 | 4.63e-01 | 0.116 |
255783 | INAFM1 | P11T-E | Human | Esophagus | ESCC | 7.67e-07 | 3.55e-01 | 0.1426 |
255783 | INAFM1 | P12T-E | Human | Esophagus | ESCC | 7.94e-18 | 2.89e-01 | 0.1122 |
255783 | INAFM1 | P15T-E | Human | Esophagus | ESCC | 6.96e-08 | 3.92e-02 | 0.1149 |
255783 | INAFM1 | P16T-E | Human | Esophagus | ESCC | 2.73e-06 | 2.52e-02 | 0.1153 |
255783 | INAFM1 | P17T-E | Human | Esophagus | ESCC | 2.74e-08 | 2.37e-01 | 0.1278 |
255783 | INAFM1 | P20T-E | Human | Esophagus | ESCC | 5.77e-22 | 4.86e-01 | 0.1124 |
255783 | INAFM1 | P21T-E | Human | Esophagus | ESCC | 4.25e-12 | 1.94e-01 | 0.1617 |
255783 | INAFM1 | P22T-E | Human | Esophagus | ESCC | 9.08e-09 | 2.22e-01 | 0.1236 |
255783 | INAFM1 | P23T-E | Human | Esophagus | ESCC | 2.09e-18 | 5.83e-01 | 0.108 |
255783 | INAFM1 | P24T-E | Human | Esophagus | ESCC | 5.11e-06 | 2.14e-01 | 0.1287 |
255783 | INAFM1 | P26T-E | Human | Esophagus | ESCC | 3.55e-25 | 5.11e-01 | 0.1276 |
255783 | INAFM1 | P27T-E | Human | Esophagus | ESCC | 3.86e-15 | 2.58e-01 | 0.1055 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
INAFM1 | SNV | Missense_Mutation | c.395N>T | p.Thr132Met | p.T132M | C9JVW0 | protein_coding | deleterious_low_confidence(0) | possibly_damaging(0.862) | TCGA-WS-AB45-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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