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Gene: HOXA11-AS |
Gene summary for HOXA11-AS |
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Gene information | Species | Human | Gene symbol | HOXA11-AS | Gene ID | 221883 |
Gene name | HOXA11 antisense RNA | |
Gene Alias | HOXA-AS5 | |
Cytomap | 7p15.2 | |
Gene Type | ncRNA | GO ID | GO:0008150 | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
221883 | HOXA11-AS | HTA11_3410_2000001011 | Human | Colorectum | AD | 1.04e-08 | -2.80e-01 | 0.0155 |
221883 | HOXA11-AS | HTA11_2487_2000001011 | Human | Colorectum | SER | 3.02e-04 | -2.80e-01 | -0.1808 |
221883 | HOXA11-AS | HTA11_1938_2000001011 | Human | Colorectum | AD | 1.11e-02 | -2.80e-01 | -0.0811 |
221883 | HOXA11-AS | HTA11_78_2000001011 | Human | Colorectum | AD | 2.90e-02 | -2.63e-01 | -0.1088 |
221883 | HOXA11-AS | HTA11_347_2000001011 | Human | Colorectum | AD | 6.08e-03 | -2.45e-01 | -0.1954 |
221883 | HOXA11-AS | HTA11_1391_2000001011 | Human | Colorectum | AD | 2.12e-03 | -2.66e-01 | -0.059 |
221883 | HOXA11-AS | HTA11_866_3004761011 | Human | Colorectum | AD | 2.43e-03 | -2.61e-01 | 0.096 |
221883 | HOXA11-AS | HTA11_7696_3000711011 | Human | Colorectum | AD | 6.68e-06 | -2.72e-01 | 0.0674 |
221883 | HOXA11-AS | HTA11_6818_2000001021 | Human | Colorectum | AD | 1.94e-02 | -2.80e-01 | 0.0588 |
221883 | HOXA11-AS | HTA11_99999970781_79442 | Human | Colorectum | MSS | 1.05e-05 | -2.77e-01 | 0.294 |
221883 | HOXA11-AS | A015-C-203 | Human | Colorectum | FAP | 7.84e-04 | -4.15e-02 | -0.1294 |
221883 | HOXA11-AS | A015-C-204 | Human | Colorectum | FAP | 7.94e-07 | -2.80e-01 | -0.0228 |
221883 | HOXA11-AS | A002-C-201 | Human | Colorectum | FAP | 7.69e-04 | -2.10e-01 | 0.0324 |
221883 | HOXA11-AS | A002-C-205 | Human | Colorectum | FAP | 1.94e-02 | 3.26e-02 | -0.1236 |
221883 | HOXA11-AS | A014-C-108 | Human | Colorectum | FAP | 3.24e-17 | 8.05e-01 | -0.124 |
221883 | HOXA11-AS | A015-C-106 | Human | Colorectum | FAP | 1.00e-04 | 2.67e-01 | -0.0511 |
221883 | HOXA11-AS | A002-C-114 | Human | Colorectum | FAP | 2.03e-02 | 1.44e-01 | -0.1561 |
221883 | HOXA11-AS | A015-C-104 | Human | Colorectum | FAP | 1.15e-05 | 1.23e-01 | -0.1899 |
221883 | HOXA11-AS | A015-C-202 | Human | Colorectum | FAP | 4.90e-22 | 7.23e-01 | -0.0849 |
221883 | HOXA11-AS | A002-C-116 | Human | Colorectum | FAP | 4.02e-03 | -1.99e-01 | -0.0452 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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