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Gene: HNF1A-AS1 |
Gene summary for HNF1A-AS1 |
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Gene information | Species | Human | Gene symbol | HNF1A-AS1 | Gene ID | 283460 |
Gene name | HNF1A antisense RNA 1 | |
Gene Alias | C12orf27 | |
Cytomap | 12q24.31 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
283460 | HNF1A-AS1 | HTA11_3410_2000001011 | Human | Colorectum | AD | 1.83e-99 | 1.59e+00 | 0.0155 |
283460 | HNF1A-AS1 | HTA11_2487_2000001011 | Human | Colorectum | SER | 2.67e-74 | 2.02e+00 | -0.1808 |
283460 | HNF1A-AS1 | HTA11_2951_2000001011 | Human | Colorectum | AD | 2.96e-39 | 1.88e+00 | 0.0216 |
283460 | HNF1A-AS1 | HTA11_1938_2000001011 | Human | Colorectum | AD | 2.78e-57 | 1.68e+00 | -0.0811 |
283460 | HNF1A-AS1 | HTA11_78_2000001011 | Human | Colorectum | AD | 2.98e-63 | 1.54e+00 | -0.1088 |
283460 | HNF1A-AS1 | HTA11_347_2000001011 | Human | Colorectum | AD | 1.27e-131 | 2.52e+00 | -0.1954 |
283460 | HNF1A-AS1 | HTA11_411_2000001011 | Human | Colorectum | SER | 3.87e-32 | 2.39e+00 | -0.2602 |
283460 | HNF1A-AS1 | HTA11_2112_2000001011 | Human | Colorectum | SER | 7.50e-21 | 1.63e+00 | -0.2196 |
283460 | HNF1A-AS1 | HTA11_3361_2000001011 | Human | Colorectum | AD | 8.62e-63 | 1.94e+00 | -0.1207 |
283460 | HNF1A-AS1 | HTA11_83_2000001011 | Human | Colorectum | SER | 2.22e-58 | 1.82e+00 | -0.1526 |
283460 | HNF1A-AS1 | HTA11_696_2000001011 | Human | Colorectum | AD | 8.90e-109 | 2.13e+00 | -0.1464 |
283460 | HNF1A-AS1 | HTA11_866_2000001011 | Human | Colorectum | AD | 6.39e-131 | 2.37e+00 | -0.1001 |
283460 | HNF1A-AS1 | HTA11_1391_2000001011 | Human | Colorectum | AD | 2.66e-87 | 2.14e+00 | -0.059 |
283460 | HNF1A-AS1 | HTA11_2992_2000001011 | Human | Colorectum | SER | 4.72e-37 | 2.26e+00 | -0.1706 |
283460 | HNF1A-AS1 | HTA11_5212_2000001011 | Human | Colorectum | AD | 1.33e-31 | 1.32e+00 | -0.2061 |
283460 | HNF1A-AS1 | HTA11_5216_2000001011 | Human | Colorectum | SER | 1.31e-28 | 1.48e+00 | -0.1462 |
283460 | HNF1A-AS1 | HTA11_546_2000001011 | Human | Colorectum | AD | 5.99e-68 | 2.54e+00 | -0.0842 |
283460 | HNF1A-AS1 | HTA11_9341_2000001011 | Human | Colorectum | SER | 4.70e-34 | 1.95e+00 | -0.00410000000000005 |
283460 | HNF1A-AS1 | HTA11_7862_2000001011 | Human | Colorectum | AD | 3.06e-51 | 1.70e+00 | -0.0179 |
283460 | HNF1A-AS1 | HTA11_866_3004761011 | Human | Colorectum | AD | 2.82e-96 | 1.83e+00 | 0.096 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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