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Gene: HAGLROS |
Gene summary for HAGLROS |
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Gene information | Species | Human | Gene symbol | HAGLROS | Gene ID | 102800310 |
Gene name | HAGLR opposite strand lncRNA | |
Gene Alias | HAGLROS | |
Cytomap | 2q31.1 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
102800310 | HAGLROS | LZE7T | Human | Esophagus | ESCC | 2.68e-16 | 7.09e-01 | 0.0667 |
102800310 | HAGLROS | P4T-E | Human | Esophagus | ESCC | 2.20e-02 | 1.20e-01 | 0.1323 |
102800310 | HAGLROS | P8T-E | Human | Esophagus | ESCC | 8.84e-05 | 1.35e-01 | 0.0889 |
102800310 | HAGLROS | P10T-E | Human | Esophagus | ESCC | 1.78e-03 | 7.79e-02 | 0.116 |
102800310 | HAGLROS | P16T-E | Human | Esophagus | ESCC | 2.02e-06 | 1.71e-01 | 0.1153 |
102800310 | HAGLROS | P19T-E | Human | Esophagus | ESCC | 7.48e-03 | 2.80e-01 | 0.1662 |
102800310 | HAGLROS | P22T-E | Human | Esophagus | ESCC | 9.56e-08 | 1.87e-01 | 0.1236 |
102800310 | HAGLROS | P23T-E | Human | Esophagus | ESCC | 7.24e-15 | 3.86e-01 | 0.108 |
102800310 | HAGLROS | P24T-E | Human | Esophagus | ESCC | 2.02e-06 | 1.63e-01 | 0.1287 |
102800310 | HAGLROS | P26T-E | Human | Esophagus | ESCC | 1.66e-02 | 8.62e-02 | 0.1276 |
102800310 | HAGLROS | P28T-E | Human | Esophagus | ESCC | 4.17e-05 | 1.37e-01 | 0.1149 |
102800310 | HAGLROS | P30T-E | Human | Esophagus | ESCC | 4.47e-24 | 7.62e-01 | 0.137 |
102800310 | HAGLROS | P32T-E | Human | Esophagus | ESCC | 1.96e-05 | 1.52e-01 | 0.1666 |
102800310 | HAGLROS | P37T-E | Human | Esophagus | ESCC | 1.24e-04 | 1.16e-01 | 0.1371 |
102800310 | HAGLROS | P47T-E | Human | Esophagus | ESCC | 9.44e-07 | 1.37e-01 | 0.1067 |
102800310 | HAGLROS | P48T-E | Human | Esophagus | ESCC | 4.44e-08 | 1.60e-01 | 0.0959 |
102800310 | HAGLROS | P52T-E | Human | Esophagus | ESCC | 4.24e-18 | 3.59e-01 | 0.1555 |
102800310 | HAGLROS | P56T-E | Human | Esophagus | ESCC | 6.66e-05 | 3.30e-01 | 0.1613 |
102800310 | HAGLROS | P57T-E | Human | Esophagus | ESCC | 5.38e-04 | 1.58e-01 | 0.0926 |
102800310 | HAGLROS | P61T-E | Human | Esophagus | ESCC | 1.72e-13 | 2.89e-01 | 0.099 |
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Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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