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Gene: GYLTL1B |
Gene summary for GYLTL1B |
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Gene information | Species | Human | Gene symbol | GYLTL1B | Gene ID | 120071 |
Gene name | LARGE xylosyl- and glucuronyltransferase 2 | |
Gene Alias | GYLTL1B | |
Cytomap | 11p11.2 | |
Gene Type | protein-coding | GO ID | GO:0006464 | UniProtAcc | Q8N3Y3 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
120071 | GYLTL1B | P1T-E | Human | Esophagus | ESCC | 1.64e-05 | 2.78e-01 | 0.0875 |
120071 | GYLTL1B | P2T-E | Human | Esophagus | ESCC | 2.85e-73 | 1.21e+00 | 0.1177 |
120071 | GYLTL1B | P4T-E | Human | Esophagus | ESCC | 1.01e-26 | 6.05e-01 | 0.1323 |
120071 | GYLTL1B | P5T-E | Human | Esophagus | ESCC | 2.86e-20 | 4.03e-01 | 0.1327 |
120071 | GYLTL1B | P8T-E | Human | Esophagus | ESCC | 2.93e-15 | 3.03e-01 | 0.0889 |
120071 | GYLTL1B | P9T-E | Human | Esophagus | ESCC | 4.38e-26 | 5.37e-01 | 0.1131 |
120071 | GYLTL1B | P10T-E | Human | Esophagus | ESCC | 2.27e-21 | 3.63e-01 | 0.116 |
120071 | GYLTL1B | P11T-E | Human | Esophagus | ESCC | 2.23e-30 | 1.43e+00 | 0.1426 |
120071 | GYLTL1B | P12T-E | Human | Esophagus | ESCC | 5.88e-35 | 6.58e-01 | 0.1122 |
120071 | GYLTL1B | P15T-E | Human | Esophagus | ESCC | 5.73e-37 | 7.60e-01 | 0.1149 |
120071 | GYLTL1B | P16T-E | Human | Esophagus | ESCC | 6.31e-48 | 7.21e-01 | 0.1153 |
120071 | GYLTL1B | P17T-E | Human | Esophagus | ESCC | 1.45e-12 | 5.22e-01 | 0.1278 |
120071 | GYLTL1B | P19T-E | Human | Esophagus | ESCC | 4.64e-06 | 4.34e-01 | 0.1662 |
120071 | GYLTL1B | P20T-E | Human | Esophagus | ESCC | 1.20e-41 | 8.80e-01 | 0.1124 |
120071 | GYLTL1B | P21T-E | Human | Esophagus | ESCC | 2.87e-41 | 8.45e-01 | 0.1617 |
120071 | GYLTL1B | P22T-E | Human | Esophagus | ESCC | 1.88e-11 | 2.37e-01 | 0.1236 |
120071 | GYLTL1B | P23T-E | Human | Esophagus | ESCC | 5.34e-19 | 4.38e-01 | 0.108 |
120071 | GYLTL1B | P24T-E | Human | Esophagus | ESCC | 3.87e-34 | 7.75e-01 | 0.1287 |
120071 | GYLTL1B | P26T-E | Human | Esophagus | ESCC | 4.09e-46 | 8.62e-01 | 0.1276 |
120071 | GYLTL1B | P27T-E | Human | Esophagus | ESCC | 3.41e-36 | 5.46e-01 | 0.1055 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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