GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:0007586 | Stomach | GC | digestion | 38/1159 | 137/18723 | 1.80e-15 | 1.22e-12 | 38 |
GO:00226006 | Stomach | GC | digestive system process | 30/1159 | 104/18723 | 5.40e-13 | 2.10e-10 | 30 |
GO:00070156 | Stomach | GC | actin filament organization | 67/1159 | 442/18723 | 7.96e-12 | 2.20e-09 | 67 |
GO:00097436 | Stomach | GC | response to carbohydrate | 40/1159 | 253/18723 | 4.13e-08 | 2.85e-06 | 40 |
GO:00342846 | Stomach | GC | response to monosaccharide | 37/1159 | 225/18723 | 4.67e-08 | 3.17e-06 | 37 |
GO:00097466 | Stomach | GC | response to hexose | 36/1159 | 219/18723 | 7.14e-08 | 4.62e-06 | 36 |
GO:00097496 | Stomach | GC | response to glucose | 33/1159 | 212/18723 | 8.93e-07 | 4.33e-05 | 33 |
GO:00316676 | Stomach | GC | response to nutrient levels | 56/1159 | 474/18723 | 2.47e-06 | 1.06e-04 | 56 |
GO:00713315 | Stomach | GC | cellular response to hexose stimulus | 25/1159 | 153/18723 | 7.68e-06 | 2.77e-04 | 25 |
GO:00713265 | Stomach | GC | cellular response to monosaccharide stimulus | 25/1159 | 154/18723 | 8.64e-06 | 2.97e-04 | 25 |
GO:00713335 | Stomach | GC | cellular response to glucose stimulus | 24/1159 | 151/18723 | 1.87e-05 | 5.77e-04 | 24 |
GO:00713225 | Stomach | GC | cellular response to carbohydrate stimulus | 25/1159 | 163/18723 | 2.36e-05 | 6.90e-04 | 25 |
GO:00425935 | Stomach | GC | glucose homeostasis | 34/1159 | 258/18723 | 2.54e-05 | 7.31e-04 | 34 |
GO:00335005 | Stomach | GC | carbohydrate homeostasis | 34/1159 | 259/18723 | 2.76e-05 | 7.80e-04 | 34 |
GO:00081546 | Stomach | GC | actin polymerization or depolymerization | 30/1159 | 218/18723 | 3.29e-05 | 8.94e-04 | 30 |
GO:19049516 | Stomach | GC | positive regulation of establishment of protein localization | 39/1159 | 319/18723 | 3.79e-05 | 9.76e-04 | 39 |
GO:00716925 | Stomach | GC | protein localization to extracellular region | 43/1159 | 368/18723 | 4.61e-05 | 1.11e-03 | 43 |
GO:00093065 | Stomach | GC | protein secretion | 42/1159 | 359/18723 | 5.46e-05 | 1.29e-03 | 42 |
GO:00355925 | Stomach | GC | establishment of protein localization to extracellular region | 42/1159 | 360/18723 | 5.82e-05 | 1.34e-03 | 42 |
GO:00016785 | Stomach | GC | cellular glucose homeostasis | 25/1159 | 172/18723 | 5.90e-05 | 1.35e-03 | 25 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
GHRL | SNV | Missense_Mutation | | c.196N>A | p.Glu66Lys | p.E66K | Q9UBU3 | protein_coding | tolerated(0.12) | possibly_damaging(0.492) | TCGA-A8-A06Q-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
GHRL | SNV | Missense_Mutation | rs767976379 | c.187N>A | p.Gly63Ser | p.G63S | Q9UBU3 | protein_coding | tolerated(0.8) | benign(0.029) | TCGA-BH-A0EB-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | arimidex | SD |
GHRL | SNV | Missense_Mutation | rs540101934 | c.40N>A | p.Gly14Ser | p.G14S | Q9UBU3 | protein_coding | tolerated(1) | benign(0) | TCGA-G4-6628-01 | Colorectum | colon adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
GHRL | SNV | Missense_Mutation | novel | c.122N>T | p.Ser41Leu | p.S41L | Q9UBU3 | protein_coding | tolerated(0.19) | possibly_damaging(0.448) | TCGA-A5-A2K5-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GHRL | SNV | Missense_Mutation | novel | c.337G>T | p.Ala113Ser | p.A113S | Q9UBU3 | protein_coding | tolerated(0.23) | benign(0.272) | TCGA-AP-A1E1-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GHRL | SNV | Missense_Mutation | novel | c.290N>T | p.Ala97Val | p.A97V | Q9UBU3 | protein_coding | tolerated(0.29) | possibly_damaging(0.809) | TCGA-AX-A1CE-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unspecific | Paclitaxel | SD |
GHRL | SNV | Missense_Mutation | rs567867101 | c.173G>A | p.Arg58His | p.R58H | Q9UBU3 | protein_coding | tolerated(0.28) | benign(0) | TCGA-EO-A3KX-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GHRL | SNV | Missense_Mutation | novel | c.122C>T | p.Ser41Leu | p.S41L | Q9UBU3 | protein_coding | tolerated(0.19) | possibly_damaging(0.448) | TCGA-FI-A2D4-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | carboplatinum | PD |
GHRL | SNV | Missense_Mutation | rs372434370 | c.208N>T | p.Asp70Tyr | p.D70Y | Q9UBU3 | protein_coding | deleterious(0) | possibly_damaging(0.905) | TCGA-PG-A915-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
GHRL | SNV | Missense_Mutation | rs756969269 | c.178G>A | p.Glu60Lys | p.E60K | Q9UBU3 | protein_coding | tolerated(0.05) | possibly_damaging(0.689) | TCGA-90-A4ED-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |