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Gene: FAM195A |
Gene summary for FAM195A |
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Gene information | Species | Human | Gene symbol | FAM195A | Gene ID | 84331 |
Gene name | MAPK regulated corepressor interacting protein 2 | |
Gene Alias | C16orf14 | |
Cytomap | 16p13.3 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | Q9BUT9 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
84331 | FAM195A | P1T-E | Human | Esophagus | ESCC | 5.75e-15 | 6.28e-01 | 0.0875 |
84331 | FAM195A | P2T-E | Human | Esophagus | ESCC | 5.03e-37 | 6.99e-01 | 0.1177 |
84331 | FAM195A | P4T-E | Human | Esophagus | ESCC | 1.25e-50 | 1.25e+00 | 0.1323 |
84331 | FAM195A | P5T-E | Human | Esophagus | ESCC | 1.24e-51 | 8.88e-01 | 0.1327 |
84331 | FAM195A | P8T-E | Human | Esophagus | ESCC | 3.22e-45 | 7.17e-01 | 0.0889 |
84331 | FAM195A | P9T-E | Human | Esophagus | ESCC | 5.15e-24 | 5.47e-01 | 0.1131 |
84331 | FAM195A | P10T-E | Human | Esophagus | ESCC | 4.24e-18 | 3.12e-01 | 0.116 |
84331 | FAM195A | P11T-E | Human | Esophagus | ESCC | 1.92e-17 | 5.50e-01 | 0.1426 |
84331 | FAM195A | P12T-E | Human | Esophagus | ESCC | 5.03e-37 | 6.16e-01 | 0.1122 |
84331 | FAM195A | P15T-E | Human | Esophagus | ESCC | 2.42e-52 | 1.07e+00 | 0.1149 |
84331 | FAM195A | P16T-E | Human | Esophagus | ESCC | 1.23e-20 | 3.62e-01 | 0.1153 |
84331 | FAM195A | P17T-E | Human | Esophagus | ESCC | 1.45e-12 | 4.69e-01 | 0.1278 |
84331 | FAM195A | P19T-E | Human | Esophagus | ESCC | 2.95e-08 | 7.21e-01 | 0.1662 |
84331 | FAM195A | P20T-E | Human | Esophagus | ESCC | 3.21e-42 | 8.53e-01 | 0.1124 |
84331 | FAM195A | P21T-E | Human | Esophagus | ESCC | 6.36e-70 | 1.22e+00 | 0.1617 |
84331 | FAM195A | P22T-E | Human | Esophagus | ESCC | 2.13e-27 | 4.68e-01 | 0.1236 |
84331 | FAM195A | P23T-E | Human | Esophagus | ESCC | 2.01e-47 | 1.14e+00 | 0.108 |
84331 | FAM195A | P24T-E | Human | Esophagus | ESCC | 2.87e-41 | 7.33e-01 | 0.1287 |
84331 | FAM195A | P26T-E | Human | Esophagus | ESCC | 2.87e-41 | 6.83e-01 | 0.1276 |
84331 | FAM195A | P27T-E | Human | Esophagus | ESCC | 6.36e-33 | 4.98e-01 | 0.1055 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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