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Gene: FAM179B |
Gene summary for FAM179B |
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Gene information | Species | Human | Gene symbol | FAM179B | Gene ID | 23116 |
Gene name | TOG array regulator of axonemal microtubules 1 | |
Gene Alias | FAM179B | |
Cytomap | 14q21.2 | |
Gene Type | protein-coding | GO ID | GO:0000226 | UniProtAcc | B4DHM7 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
23116 | FAM179B | P1T-E | Human | Esophagus | ESCC | 3.41e-04 | 2.16e-01 | 0.0875 |
23116 | FAM179B | P2T-E | Human | Esophagus | ESCC | 2.52e-20 | 3.89e-01 | 0.1177 |
23116 | FAM179B | P4T-E | Human | Esophagus | ESCC | 1.88e-12 | 3.09e-01 | 0.1323 |
23116 | FAM179B | P5T-E | Human | Esophagus | ESCC | 1.96e-23 | 3.14e-01 | 0.1327 |
23116 | FAM179B | P8T-E | Human | Esophagus | ESCC | 8.67e-17 | 3.30e-01 | 0.0889 |
23116 | FAM179B | P9T-E | Human | Esophagus | ESCC | 1.52e-09 | 1.53e-01 | 0.1131 |
23116 | FAM179B | P10T-E | Human | Esophagus | ESCC | 4.96e-29 | 4.67e-01 | 0.116 |
23116 | FAM179B | P11T-E | Human | Esophagus | ESCC | 1.40e-11 | 5.07e-01 | 0.1426 |
23116 | FAM179B | P12T-E | Human | Esophagus | ESCC | 1.05e-31 | 5.98e-01 | 0.1122 |
23116 | FAM179B | P15T-E | Human | Esophagus | ESCC | 6.68e-40 | 8.09e-01 | 0.1149 |
23116 | FAM179B | P16T-E | Human | Esophagus | ESCC | 2.82e-25 | 4.69e-01 | 0.1153 |
23116 | FAM179B | P17T-E | Human | Esophagus | ESCC | 2.70e-04 | 2.72e-01 | 0.1278 |
23116 | FAM179B | P20T-E | Human | Esophagus | ESCC | 1.46e-15 | 2.93e-01 | 0.1124 |
23116 | FAM179B | P21T-E | Human | Esophagus | ESCC | 2.43e-07 | 1.03e-01 | 0.1617 |
23116 | FAM179B | P22T-E | Human | Esophagus | ESCC | 1.64e-11 | 2.02e-01 | 0.1236 |
23116 | FAM179B | P23T-E | Human | Esophagus | ESCC | 2.52e-17 | 3.39e-01 | 0.108 |
23116 | FAM179B | P24T-E | Human | Esophagus | ESCC | 2.45e-08 | 1.52e-01 | 0.1287 |
23116 | FAM179B | P26T-E | Human | Esophagus | ESCC | 1.23e-41 | 6.77e-01 | 0.1276 |
23116 | FAM179B | P27T-E | Human | Esophagus | ESCC | 3.07e-35 | 6.22e-01 | 0.1055 |
23116 | FAM179B | P28T-E | Human | Esophagus | ESCC | 1.83e-12 | 2.42e-01 | 0.1149 |
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Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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