|
Gene: ENTPD3-AS1 |
Gene summary for ENTPD3-AS1 |
Gene summary. |
Gene information | Species | Human | Gene symbol | ENTPD3-AS1 | Gene ID | 285266 |
Gene name | ENTPD3 antisense RNA 1 | |
Gene Alias | ENTPD3-AS1 | |
Cytomap | 3p22.1 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
Top |
Malignant transformation analysis |
Identification of the aberrant gene expression in precancerous and cancerous lesions by comparing the gene expression of stem-like cells in diseased tissues with normal stem cells |
Malignant transformation involving gene list. |
Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
285266 | ENTPD3-AS1 | P2T-E | Human | Esophagus | ESCC | 4.29e-05 | 6.27e-02 | 0.1177 |
285266 | ENTPD3-AS1 | P4T-E | Human | Esophagus | ESCC | 6.34e-05 | 1.06e-01 | 0.1323 |
285266 | ENTPD3-AS1 | P5T-E | Human | Esophagus | ESCC | 3.43e-03 | 2.98e-02 | 0.1327 |
285266 | ENTPD3-AS1 | P9T-E | Human | Esophagus | ESCC | 6.17e-06 | 1.19e-01 | 0.1131 |
285266 | ENTPD3-AS1 | P12T-E | Human | Esophagus | ESCC | 1.11e-02 | 6.96e-02 | 0.1122 |
285266 | ENTPD3-AS1 | P16T-E | Human | Esophagus | ESCC | 7.04e-04 | 7.28e-02 | 0.1153 |
285266 | ENTPD3-AS1 | P17T-E | Human | Esophagus | ESCC | 1.32e-03 | 1.84e-01 | 0.1278 |
285266 | ENTPD3-AS1 | P21T-E | Human | Esophagus | ESCC | 7.11e-07 | 1.41e-01 | 0.1617 |
285266 | ENTPD3-AS1 | P22T-E | Human | Esophagus | ESCC | 4.79e-06 | 6.65e-02 | 0.1236 |
285266 | ENTPD3-AS1 | P23T-E | Human | Esophagus | ESCC | 3.18e-05 | 1.70e-01 | 0.108 |
285266 | ENTPD3-AS1 | P24T-E | Human | Esophagus | ESCC | 4.51e-04 | 7.27e-02 | 0.1287 |
285266 | ENTPD3-AS1 | P26T-E | Human | Esophagus | ESCC | 6.43e-03 | 5.19e-02 | 0.1276 |
285266 | ENTPD3-AS1 | P27T-E | Human | Esophagus | ESCC | 8.82e-05 | 6.56e-02 | 0.1055 |
285266 | ENTPD3-AS1 | P28T-E | Human | Esophagus | ESCC | 1.58e-02 | 5.69e-02 | 0.1149 |
285266 | ENTPD3-AS1 | P30T-E | Human | Esophagus | ESCC | 4.71e-04 | 1.93e-01 | 0.137 |
285266 | ENTPD3-AS1 | P32T-E | Human | Esophagus | ESCC | 5.32e-10 | 1.00e-01 | 0.1666 |
285266 | ENTPD3-AS1 | P36T-E | Human | Esophagus | ESCC | 8.12e-03 | 8.48e-02 | 0.1187 |
285266 | ENTPD3-AS1 | P39T-E | Human | Esophagus | ESCC | 1.25e-04 | 1.05e-01 | 0.0894 |
285266 | ENTPD3-AS1 | P40T-E | Human | Esophagus | ESCC | 2.22e-02 | 8.73e-02 | 0.109 |
285266 | ENTPD3-AS1 | P57T-E | Human | Esophagus | ESCC | 3.75e-11 | 9.61e-02 | 0.0926 |
Page: 1 2 |
Transcriptomic changes along malignancy continuum. |
Tissue | Expression Dynamics | Abbreviation |
Esophagus | ESCC: Esophageal squamous cell carcinoma | |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
Top |
Malignant transformation related pathway analysis |
Find out the enriched GO biological processes and KEGG pathways involved in transition from healthy to precancer to cancer |
Figure of enriched GO biological processes. |
Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | |
Colorectum | SER | |
Colorectum | MSS | |
Colorectum | MSI-H | |
Colorectum | FAP |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
Enriched GO biological processes. |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
Enriched KEGG pathways. |
Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
Top |
Cell-cell communication analysis |
Identification of potential cell-cell interactions between two cell types and their ligand-receptor pairs for different disease states |
Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
Top |
Single-cell gene regulatory network inference analysis |
Find out the significant the regulons (TFs) and the target genes of each regulon across cell types for different disease states |
TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
Top |
Somatic mutation of malignant transformation related genes |
Annotation of somatic variants for genes involved in malignant transformation |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
Top |
Related drugs of malignant transformation related genes |
Identification of chemicals and drugs interact with genes involved in malignant transfromation |
(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |