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Gene: ELFN1-AS1 |
Gene summary for ELFN1-AS1 |
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Gene information | Species | Human | Gene symbol | ELFN1-AS1 | Gene ID | 101927125 |
Gene name | ELFN1 antisense RNA 1 | |
Gene Alias | MYCLo-2 | |
Cytomap | 7p22.3 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
101927125 | ELFN1-AS1 | LZE22T | Human | Esophagus | ESCC | 1.15e-08 | 3.89e-01 | 0.068 |
101927125 | ELFN1-AS1 | P9T-E | Human | Esophagus | ESCC | 8.59e-07 | 1.76e-01 | 0.1131 |
101927125 | ELFN1-AS1 | P24T-E | Human | Esophagus | ESCC | 4.44e-08 | 1.85e-01 | 0.1287 |
101927125 | ELFN1-AS1 | P54T-E | Human | Esophagus | ESCC | 2.11e-02 | 1.23e-01 | 0.0975 |
101927125 | ELFN1-AS1 | P74T-E | Human | Esophagus | ESCC | 5.32e-11 | 3.49e-01 | 0.1479 |
101927125 | ELFN1-AS1 | P75T-E | Human | Esophagus | ESCC | 1.78e-03 | 1.02e-01 | 0.1125 |
101927125 | ELFN1-AS1 | P128T-E | Human | Esophagus | ESCC | 6.78e-38 | 1.02e+00 | 0.1241 |
101927125 | ELFN1-AS1 | P130T-E | Human | Esophagus | ESCC | 6.38e-31 | 6.25e-01 | 0.1676 |
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Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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