![]() |
|||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: EFTUD1 |
Gene summary for EFTUD1 |
![]() |
Gene information | Species | Human | Gene symbol | EFTUD1 | Gene ID | 79631 |
Gene name | elongation factor like GTPase 1 | |
Gene Alias | EFTUD1 | |
Cytomap | 15q25.2 | |
Gene Type | protein-coding | GO ID | GO:0006139 | UniProtAcc | Q7Z2Z2 |
Top |
Malignant transformation analysis |
![]() |
![]() |
Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
79631 | EFTUD1 | P1T-E | Human | Esophagus | ESCC | 1.09e-04 | 2.41e-01 | 0.0875 |
79631 | EFTUD1 | P2T-E | Human | Esophagus | ESCC | 1.76e-12 | 2.26e-01 | 0.1177 |
79631 | EFTUD1 | P4T-E | Human | Esophagus | ESCC | 2.45e-12 | 2.79e-01 | 0.1323 |
79631 | EFTUD1 | P8T-E | Human | Esophagus | ESCC | 2.02e-06 | 1.66e-01 | 0.0889 |
79631 | EFTUD1 | P9T-E | Human | Esophagus | ESCC | 1.11e-03 | 1.35e-01 | 0.1131 |
79631 | EFTUD1 | P10T-E | Human | Esophagus | ESCC | 4.41e-07 | 1.51e-01 | 0.116 |
79631 | EFTUD1 | P11T-E | Human | Esophagus | ESCC | 1.72e-04 | 2.08e-01 | 0.1426 |
79631 | EFTUD1 | P12T-E | Human | Esophagus | ESCC | 4.17e-05 | 1.45e-01 | 0.1122 |
79631 | EFTUD1 | P15T-E | Human | Esophagus | ESCC | 3.12e-08 | 2.03e-01 | 0.1149 |
79631 | EFTUD1 | P16T-E | Human | Esophagus | ESCC | 1.85e-18 | 3.24e-01 | 0.1153 |
79631 | EFTUD1 | P17T-E | Human | Esophagus | ESCC | 8.50e-05 | 2.38e-01 | 0.1278 |
79631 | EFTUD1 | P20T-E | Human | Esophagus | ESCC | 1.17e-04 | 1.27e-01 | 0.1124 |
79631 | EFTUD1 | P21T-E | Human | Esophagus | ESCC | 4.44e-08 | 1.76e-01 | 0.1617 |
79631 | EFTUD1 | P22T-E | Human | Esophagus | ESCC | 4.31e-06 | 1.65e-01 | 0.1236 |
79631 | EFTUD1 | P23T-E | Human | Esophagus | ESCC | 2.13e-09 | 2.21e-01 | 0.108 |
79631 | EFTUD1 | P24T-E | Human | Esophagus | ESCC | 1.78e-03 | 1.06e-01 | 0.1287 |
79631 | EFTUD1 | P26T-E | Human | Esophagus | ESCC | 4.44e-08 | 2.01e-01 | 0.1276 |
79631 | EFTUD1 | P27T-E | Human | Esophagus | ESCC | 3.50e-02 | 1.19e-01 | 0.1055 |
79631 | EFTUD1 | P28T-E | Human | Esophagus | ESCC | 4.41e-07 | 1.75e-01 | 0.1149 |
79631 | EFTUD1 | P30T-E | Human | Esophagus | ESCC | 1.56e-12 | 3.80e-01 | 0.137 |
Page: 1 2 3 |
![]() |
Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
Top |
Malignant transformation related pathway analysis |
![]() |
![]() |
Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
![]() |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
![]() |
Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
Top |
Cell-cell communication analysis |
![]() |
Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
Top |
Single-cell gene regulatory network inference analysis |
![]() |
TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
Top |
Somatic mutation of malignant transformation related genes |
![]() |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
Top |
Related drugs of malignant transformation related genes |
![]() |
(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |