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Gene: DSG1-AS1 |
Gene summary for DSG1-AS1 |
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Gene information | Species | Human | Gene symbol | DSG1-AS1 | Gene ID | 101927718 |
Gene name | DSG1 antisense RNA 1 | |
Gene Alias | DSG1-AS1 | |
Cytomap | 18q12.1 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
101927718 | DSG1-AS1 | LZE20T | Human | Esophagus | ESCC | 7.90e-04 | 1.47e-01 | 0.0662 |
101927718 | DSG1-AS1 | P4T-E | Human | Esophagus | ESCC | 3.21e-33 | 8.89e-01 | 0.1323 |
101927718 | DSG1-AS1 | P8T-E | Human | Esophagus | ESCC | 3.28e-14 | 2.47e-01 | 0.0889 |
101927718 | DSG1-AS1 | P9T-E | Human | Esophagus | ESCC | 8.38e-03 | 1.09e-01 | 0.1131 |
101927718 | DSG1-AS1 | P12T-E | Human | Esophagus | ESCC | 2.02e-06 | 1.65e-01 | 0.1122 |
101927718 | DSG1-AS1 | P15T-E | Human | Esophagus | ESCC | 7.99e-08 | 1.69e-01 | 0.1149 |
101927718 | DSG1-AS1 | P20T-E | Human | Esophagus | ESCC | 2.17e-39 | 8.77e-01 | 0.1124 |
101927718 | DSG1-AS1 | P23T-E | Human | Esophagus | ESCC | 7.24e-15 | 3.57e-01 | 0.108 |
101927718 | DSG1-AS1 | P27T-E | Human | Esophagus | ESCC | 4.30e-10 | 2.53e-01 | 0.1055 |
101927718 | DSG1-AS1 | P30T-E | Human | Esophagus | ESCC | 4.84e-02 | 1.13e-01 | 0.137 |
101927718 | DSG1-AS1 | P32T-E | Human | Esophagus | ESCC | 8.40e-04 | 1.09e-01 | 0.1666 |
101927718 | DSG1-AS1 | P36T-E | Human | Esophagus | ESCC | 2.82e-02 | 1.02e-01 | 0.1187 |
101927718 | DSG1-AS1 | P54T-E | Human | Esophagus | ESCC | 9.92e-04 | 1.24e-01 | 0.0975 |
101927718 | DSG1-AS1 | P61T-E | Human | Esophagus | ESCC | 1.48e-02 | 1.04e-01 | 0.099 |
101927718 | DSG1-AS1 | P62T-E | Human | Esophagus | ESCC | 3.35e-17 | 3.10e-01 | 0.1302 |
101927718 | DSG1-AS1 | P75T-E | Human | Esophagus | ESCC | 2.06e-08 | 1.75e-01 | 0.1125 |
101927718 | DSG1-AS1 | P80T-E | Human | Esophagus | ESCC | 8.11e-14 | 5.95e-01 | 0.155 |
101927718 | DSG1-AS1 | P83T-E | Human | Esophagus | ESCC | 3.17e-02 | 1.10e-01 | 0.1738 |
101927718 | DSG1-AS1 | P91T-E | Human | Esophagus | ESCC | 8.74e-05 | 3.16e-01 | 0.1828 |
101927718 | DSG1-AS1 | P107T-E | Human | Esophagus | ESCC | 3.51e-03 | 1.03e-01 | 0.171 |
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Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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