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Gene: DNAI4 |
Gene summary for DNAI4 |
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Gene information | Species | Human | Gene symbol | DNAI4 | Gene ID | 79819 |
Gene name | dynein axonemal intermediate chain 4 | |
Gene Alias | DIC4 | |
Cytomap | 1p31.3 | |
Gene Type | protein-coding | GO ID | GO:0000226 | UniProtAcc | A0AVI9 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
79819 | DNAI4 | HTA11_3410_2000001011 | Human | Colorectum | AD | 3.47e-03 | 1.03e-01 | 0.0155 |
79819 | DNAI4 | HTA11_2487_2000001011 | Human | Colorectum | SER | 7.90e-11 | 3.48e-01 | -0.1808 |
79819 | DNAI4 | HTA11_1938_2000001011 | Human | Colorectum | AD | 1.83e-13 | 4.61e-01 | -0.0811 |
79819 | DNAI4 | HTA11_78_2000001011 | Human | Colorectum | AD | 4.79e-18 | 4.73e-01 | -0.1088 |
79819 | DNAI4 | HTA11_347_2000001011 | Human | Colorectum | AD | 1.95e-38 | 7.79e-01 | -0.1954 |
79819 | DNAI4 | HTA11_3361_2000001011 | Human | Colorectum | AD | 2.57e-07 | 2.46e-01 | -0.1207 |
79819 | DNAI4 | HTA11_83_2000001011 | Human | Colorectum | SER | 1.46e-11 | 3.95e-01 | -0.1526 |
79819 | DNAI4 | HTA11_696_2000001011 | Human | Colorectum | AD | 3.31e-19 | 3.75e-01 | -0.1464 |
79819 | DNAI4 | HTA11_866_2000001011 | Human | Colorectum | AD | 3.52e-13 | 3.63e-01 | -0.1001 |
79819 | DNAI4 | HTA11_1391_2000001011 | Human | Colorectum | AD | 8.44e-14 | 3.32e-01 | -0.059 |
79819 | DNAI4 | HTA11_2992_2000001011 | Human | Colorectum | SER | 1.51e-04 | 2.87e-01 | -0.1706 |
79819 | DNAI4 | HTA11_5212_2000001011 | Human | Colorectum | AD | 3.97e-04 | 2.15e-01 | -0.2061 |
79819 | DNAI4 | HTA11_5216_2000001011 | Human | Colorectum | SER | 3.22e-05 | 3.36e-01 | -0.1462 |
79819 | DNAI4 | HTA11_546_2000001011 | Human | Colorectum | AD | 1.44e-03 | 1.68e-01 | -0.0842 |
79819 | DNAI4 | HTA11_7862_2000001011 | Human | Colorectum | AD | 4.79e-05 | 2.70e-01 | -0.0179 |
79819 | DNAI4 | HTA11_866_3004761011 | Human | Colorectum | AD | 1.00e-02 | 1.18e-01 | 0.096 |
79819 | DNAI4 | HTA11_4255_2000001011 | Human | Colorectum | SER | 3.40e-02 | 2.22e-01 | 0.0446 |
79819 | DNAI4 | HTA11_7663_2000001011 | Human | Colorectum | SER | 6.81e-04 | 2.84e-01 | 0.0131 |
79819 | DNAI4 | HTA11_10623_2000001011 | Human | Colorectum | AD | 4.46e-06 | 3.00e-01 | -0.0177 |
79819 | DNAI4 | HTA11_10711_2000001011 | Human | Colorectum | AD | 6.02e-03 | 2.02e-01 | 0.0338 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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