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Gene: DIPK1A |
Gene summary for DIPK1A |
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Gene information | Species | Human | Gene symbol | DIPK1A | Gene ID | 388650 |
Gene name | divergent protein kinase domain 1A | |
Gene Alias | FAM69A | |
Cytomap | 1p22.1 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | Q5T7M9 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
388650 | DIPK1A | HTA11_3410_2000001011 | Human | Colorectum | AD | 1.23e-04 | 1.28e-01 | 0.0155 |
388650 | DIPK1A | HTA11_2487_2000001011 | Human | Colorectum | SER | 1.32e-08 | 2.75e-01 | -0.1808 |
388650 | DIPK1A | HTA11_1938_2000001011 | Human | Colorectum | AD | 3.85e-14 | 3.82e-01 | -0.0811 |
388650 | DIPK1A | HTA11_78_2000001011 | Human | Colorectum | AD | 3.40e-20 | 4.61e-01 | -0.1088 |
388650 | DIPK1A | HTA11_347_2000001011 | Human | Colorectum | AD | 2.45e-20 | 4.15e-01 | -0.1954 |
388650 | DIPK1A | HTA11_411_2000001011 | Human | Colorectum | SER | 4.01e-04 | 3.31e-01 | -0.2602 |
388650 | DIPK1A | HTA11_2112_2000001011 | Human | Colorectum | SER | 1.90e-02 | 2.76e-01 | -0.2196 |
388650 | DIPK1A | HTA11_83_2000001011 | Human | Colorectum | SER | 1.47e-06 | 3.09e-01 | -0.1526 |
388650 | DIPK1A | HTA11_696_2000001011 | Human | Colorectum | AD | 1.58e-13 | 3.12e-01 | -0.1464 |
388650 | DIPK1A | HTA11_866_2000001011 | Human | Colorectum | AD | 2.83e-15 | 3.34e-01 | -0.1001 |
388650 | DIPK1A | HTA11_1391_2000001011 | Human | Colorectum | AD | 1.17e-15 | 3.77e-01 | -0.059 |
388650 | DIPK1A | HTA11_2992_2000001011 | Human | Colorectum | SER | 1.94e-06 | 3.33e-01 | -0.1706 |
388650 | DIPK1A | HTA11_546_2000001011 | Human | Colorectum | AD | 1.74e-13 | 4.02e-01 | -0.0842 |
388650 | DIPK1A | HTA11_866_3004761011 | Human | Colorectum | AD | 9.03e-07 | 1.89e-01 | 0.096 |
388650 | DIPK1A | HTA11_8622_2000001021 | Human | Colorectum | SER | 3.19e-02 | 1.62e-01 | 0.0528 |
388650 | DIPK1A | HTA11_10623_2000001011 | Human | Colorectum | AD | 1.08e-15 | 4.69e-01 | -0.0177 |
388650 | DIPK1A | HTA11_7696_3000711011 | Human | Colorectum | AD | 9.36e-06 | 1.63e-01 | 0.0674 |
388650 | DIPK1A | HTA11_6818_2000001011 | Human | Colorectum | AD | 4.13e-05 | 3.60e-01 | 0.0112 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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