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Gene: DGUOK-AS1 |
Gene summary for DGUOK-AS1 |
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Gene information | Species | Human | Gene symbol | DGUOK-AS1 | Gene ID | 100874048 |
Gene name | DGUOK antisense RNA 1 | |
Gene Alias | DGUOK-AS1 | |
Cytomap | 2p13.1 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100874048 | DGUOK-AS1 | LZE4T | Human | Esophagus | ESCC | 3.52e-02 | 5.41e-02 | 0.0811 |
100874048 | DGUOK-AS1 | LZE7T | Human | Esophagus | ESCC | 6.01e-03 | 1.65e-01 | 0.0667 |
100874048 | DGUOK-AS1 | LZE24T | Human | Esophagus | ESCC | 3.98e-03 | 2.65e-03 | 0.0596 |
100874048 | DGUOK-AS1 | P4T-E | Human | Esophagus | ESCC | 1.22e-16 | 2.79e-01 | 0.1323 |
100874048 | DGUOK-AS1 | P9T-E | Human | Esophagus | ESCC | 1.93e-14 | 9.58e-02 | 0.1131 |
100874048 | DGUOK-AS1 | P10T-E | Human | Esophagus | ESCC | 5.57e-03 | 3.86e-02 | 0.116 |
100874048 | DGUOK-AS1 | P12T-E | Human | Esophagus | ESCC | 2.20e-04 | 1.28e-01 | 0.1122 |
100874048 | DGUOK-AS1 | P15T-E | Human | Esophagus | ESCC | 4.46e-05 | 8.54e-02 | 0.1149 |
100874048 | DGUOK-AS1 | P16T-E | Human | Esophagus | ESCC | 2.90e-02 | -1.05e-02 | 0.1153 |
100874048 | DGUOK-AS1 | P20T-E | Human | Esophagus | ESCC | 9.94e-11 | 1.54e-01 | 0.1124 |
100874048 | DGUOK-AS1 | P21T-E | Human | Esophagus | ESCC | 8.44e-08 | 2.06e-01 | 0.1617 |
100874048 | DGUOK-AS1 | P22T-E | Human | Esophagus | ESCC | 3.50e-12 | 1.83e-01 | 0.1236 |
100874048 | DGUOK-AS1 | P23T-E | Human | Esophagus | ESCC | 4.82e-11 | 2.37e-01 | 0.108 |
100874048 | DGUOK-AS1 | P24T-E | Human | Esophagus | ESCC | 5.74e-07 | 1.52e-02 | 0.1287 |
100874048 | DGUOK-AS1 | P26T-E | Human | Esophagus | ESCC | 7.50e-12 | 2.17e-01 | 0.1276 |
100874048 | DGUOK-AS1 | P27T-E | Human | Esophagus | ESCC | 6.89e-13 | 1.80e-01 | 0.1055 |
100874048 | DGUOK-AS1 | P28T-E | Human | Esophagus | ESCC | 6.11e-22 | 5.13e-01 | 0.1149 |
100874048 | DGUOK-AS1 | P30T-E | Human | Esophagus | ESCC | 4.50e-08 | 4.05e-01 | 0.137 |
100874048 | DGUOK-AS1 | P37T-E | Human | Esophagus | ESCC | 1.42e-04 | 6.73e-02 | 0.1371 |
100874048 | DGUOK-AS1 | P39T-E | Human | Esophagus | ESCC | 6.78e-08 | 1.35e-01 | 0.0894 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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