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Gene: CRYBG1 |
Gene summary for CRYBG1 |
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Gene information | Species | Human | Gene symbol | CRYBG1 | Gene ID | 202 |
Gene name | crystallin beta-gamma domain containing 1 | |
Gene Alias | AIM1 | |
Cytomap | 6q21 | |
Gene Type | protein-coding | GO ID | GO:0008150 | UniProtAcc | B3KPT0 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
202 | CRYBG1 | N_HPV_2 | Human | Cervix | N_HPV | 1.76e-04 | 2.23e-01 | -0.0131 |
202 | CRYBG1 | CCI_2 | Human | Cervix | CC | 5.30e-05 | 6.87e-01 | 0.5249 |
202 | CRYBG1 | CCI_3 | Human | Cervix | CC | 1.26e-20 | 1.44e+00 | 0.516 |
202 | CRYBG1 | Tumor | Human | Cervix | CC | 9.00e-07 | -1.86e-01 | 0.1241 |
202 | CRYBG1 | sample3 | Human | Cervix | CC | 2.01e-17 | 4.58e-01 | 0.1387 |
202 | CRYBG1 | T3 | Human | Cervix | CC | 1.46e-16 | 4.52e-01 | 0.1389 |
202 | CRYBG1 | HTA11_347_2000001011 | Human | Colorectum | AD | 2.92e-12 | 7.36e-01 | -0.1954 |
202 | CRYBG1 | HTA11_1391_2000001011 | Human | Colorectum | AD | 2.12e-03 | 6.92e-01 | -0.059 |
202 | CRYBG1 | HTA11_99999970781_79442 | Human | Colorectum | MSS | 3.94e-62 | -9.22e-01 | 0.294 |
202 | CRYBG1 | HTA11_99999965062_69753 | Human | Colorectum | MSI-H | 3.17e-02 | -9.22e-01 | 0.3487 |
202 | CRYBG1 | HTA11_99999965104_69814 | Human | Colorectum | MSS | 2.31e-23 | -9.22e-01 | 0.281 |
202 | CRYBG1 | HTA11_99999971662_82457 | Human | Colorectum | MSS | 1.40e-59 | -9.22e-01 | 0.3859 |
202 | CRYBG1 | HTA11_99999973899_84307 | Human | Colorectum | MSS | 2.30e-18 | -9.22e-01 | 0.2585 |
202 | CRYBG1 | HTA11_99999974143_84620 | Human | Colorectum | MSS | 1.29e-61 | -9.22e-01 | 0.3005 |
202 | CRYBG1 | F007 | Human | Colorectum | FAP | 5.05e-04 | -3.19e-01 | 0.1176 |
202 | CRYBG1 | A001-C-207 | Human | Colorectum | FAP | 5.38e-05 | -2.81e-01 | 0.1278 |
202 | CRYBG1 | A015-C-203 | Human | Colorectum | FAP | 8.52e-36 | -3.28e-01 | -0.1294 |
202 | CRYBG1 | A015-C-204 | Human | Colorectum | FAP | 2.56e-08 | -1.61e-01 | -0.0228 |
202 | CRYBG1 | A014-C-040 | Human | Colorectum | FAP | 2.66e-04 | -2.44e-01 | -0.1184 |
202 | CRYBG1 | A002-C-201 | Human | Colorectum | FAP | 3.45e-13 | -8.90e-02 | 0.0324 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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