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Gene: COX10-AS1 |
Gene summary for COX10-AS1 |
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Gene information | Species | Human | Gene symbol | COX10-AS1 | Gene ID | 100874058 |
Gene name | COX10 divergent transcript | |
Gene Alias | COX10-AS | |
Cytomap | 17p12 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100874058 | COX10-AS1 | CCI_1 | Human | Cervix | CC | 1.49e-06 | 2.97e-01 | 0.528 |
100874058 | COX10-AS1 | CCI_2 | Human | Cervix | CC | 1.69e-09 | 5.01e-01 | 0.5249 |
100874058 | COX10-AS1 | CCI_3 | Human | Cervix | CC | 4.60e-08 | 2.74e-01 | 0.516 |
100874058 | COX10-AS1 | HTA11_2487_2000001011 | Human | Colorectum | SER | 3.37e-03 | 1.89e-01 | -0.1808 |
100874058 | COX10-AS1 | HTA11_78_2000001011 | Human | Colorectum | AD | 2.58e-08 | 2.27e-01 | -0.1088 |
100874058 | COX10-AS1 | HTA11_347_2000001011 | Human | Colorectum | AD | 8.02e-16 | 3.56e-01 | -0.1954 |
100874058 | COX10-AS1 | HTA11_3361_2000001011 | Human | Colorectum | AD | 5.46e-03 | 1.46e-01 | -0.1207 |
100874058 | COX10-AS1 | HTA11_83_2000001011 | Human | Colorectum | SER | 1.47e-06 | 2.18e-01 | -0.1526 |
100874058 | COX10-AS1 | HTA11_696_2000001011 | Human | Colorectum | AD | 4.40e-09 | 2.13e-01 | -0.1464 |
100874058 | COX10-AS1 | HTA11_866_2000001011 | Human | Colorectum | AD | 1.96e-10 | 2.13e-01 | -0.1001 |
100874058 | COX10-AS1 | HTA11_1391_2000001011 | Human | Colorectum | AD | 6.11e-08 | 2.44e-01 | -0.059 |
100874058 | COX10-AS1 | HTA11_546_2000001011 | Human | Colorectum | AD | 2.65e-04 | 2.15e-01 | -0.0842 |
100874058 | COX10-AS1 | HTA11_7862_2000001011 | Human | Colorectum | AD | 3.08e-04 | 2.16e-01 | -0.0179 |
100874058 | COX10-AS1 | HTA11_866_3004761011 | Human | Colorectum | AD | 6.26e-04 | 1.42e-01 | 0.096 |
100874058 | COX10-AS1 | HTA11_10623_2000001011 | Human | Colorectum | AD | 8.81e-15 | 5.92e-01 | -0.0177 |
100874058 | COX10-AS1 | HTA11_10711_2000001011 | Human | Colorectum | AD | 9.64e-06 | 2.02e-01 | 0.0338 |
100874058 | COX10-AS1 | HTA11_7696_3000711011 | Human | Colorectum | AD | 3.83e-12 | 2.85e-01 | 0.0674 |
100874058 | COX10-AS1 | HTA11_6818_2000001021 | Human | Colorectum | AD | 4.99e-02 | 1.32e-01 | 0.0588 |
100874058 | COX10-AS1 | HTA11_99999970781_79442 | Human | Colorectum | MSS | 9.55e-09 | 2.25e-01 | 0.294 |
100874058 | COX10-AS1 | HTA11_99999965062_69753 | Human | Colorectum | MSI-H | 7.89e-03 | 3.22e-01 | 0.3487 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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