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Gene: C9orf9 |
Gene summary for C9ORF9 |
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Gene information | Species | Human | Gene symbol | C9orf9 | Gene ID | 11092 |
Gene name | sperm acrosome associated 9 | |
Gene Alias | C9orf9 | |
Cytomap | 9q34.13 | |
Gene Type | protein-coding | GO ID | GO:0001669 | UniProtAcc | A0A024R8F2 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
11092 | C9orf9 | P2T-E | Human | Esophagus | ESCC | 2.39e-24 | 4.06e-01 | 0.1177 |
11092 | C9orf9 | P4T-E | Human | Esophagus | ESCC | 1.22e-08 | 1.96e-01 | 0.1323 |
11092 | C9orf9 | P5T-E | Human | Esophagus | ESCC | 4.30e-10 | 2.00e-01 | 0.1327 |
11092 | C9orf9 | P8T-E | Human | Esophagus | ESCC | 2.03e-09 | 1.96e-01 | 0.0889 |
11092 | C9orf9 | P9T-E | Human | Esophagus | ESCC | 3.67e-14 | 2.96e-01 | 0.1131 |
11092 | C9orf9 | P10T-E | Human | Esophagus | ESCC | 4.40e-09 | 2.10e-01 | 0.116 |
11092 | C9orf9 | P11T-E | Human | Esophagus | ESCC | 3.25e-05 | 2.37e-01 | 0.1426 |
11092 | C9orf9 | P12T-E | Human | Esophagus | ESCC | 1.96e-05 | 1.52e-01 | 0.1122 |
11092 | C9orf9 | P15T-E | Human | Esophagus | ESCC | 5.83e-12 | 2.52e-01 | 0.1149 |
11092 | C9orf9 | P16T-E | Human | Esophagus | ESCC | 5.79e-16 | 2.88e-01 | 0.1153 |
11092 | C9orf9 | P17T-E | Human | Esophagus | ESCC | 8.50e-05 | 2.22e-01 | 0.1278 |
11092 | C9orf9 | P20T-E | Human | Esophagus | ESCC | 1.61e-08 | 2.08e-01 | 0.1124 |
11092 | C9orf9 | P21T-E | Human | Esophagus | ESCC | 2.41e-29 | 5.36e-01 | 0.1617 |
11092 | C9orf9 | P22T-E | Human | Esophagus | ESCC | 3.02e-26 | 4.55e-01 | 0.1236 |
11092 | C9orf9 | P23T-E | Human | Esophagus | ESCC | 9.87e-03 | 1.11e-01 | 0.108 |
11092 | C9orf9 | P24T-E | Human | Esophagus | ESCC | 1.13e-16 | 2.70e-01 | 0.1287 |
11092 | C9orf9 | P26T-E | Human | Esophagus | ESCC | 9.02e-11 | 2.65e-01 | 0.1276 |
11092 | C9orf9 | P27T-E | Human | Esophagus | ESCC | 4.41e-07 | 1.58e-01 | 0.1055 |
11092 | C9orf9 | P28T-E | Human | Esophagus | ESCC | 2.06e-08 | 1.71e-01 | 0.1149 |
11092 | C9orf9 | P30T-E | Human | Esophagus | ESCC | 4.41e-11 | 3.43e-01 | 0.137 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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