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Gene: APTR |
Gene summary for APTR |
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Gene information | Species | Human | Gene symbol | APTR | Gene ID | 100505854 |
Gene name | Alu-mediated CDKN1A/p21 transcriptional regulator | |
Gene Alias | RSBN1L-AS1 | |
Cytomap | 7q11.23 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100505854 | APTR | HTA11_347_2000001011 | Human | Colorectum | AD | 1.85e-02 | 3.80e-01 | -0.1954 |
100505854 | APTR | A001-C-207 | Human | Colorectum | FAP | 7.05e-05 | -2.59e-01 | 0.1278 |
100505854 | APTR | A015-C-203 | Human | Colorectum | FAP | 1.40e-08 | -2.29e-01 | -0.1294 |
100505854 | APTR | A015-C-204 | Human | Colorectum | FAP | 2.13e-03 | -2.12e-01 | -0.0228 |
100505854 | APTR | A002-C-201 | Human | Colorectum | FAP | 9.54e-08 | -2.58e-01 | 0.0324 |
100505854 | APTR | A001-C-119 | Human | Colorectum | FAP | 9.15e-04 | -2.09e-01 | -0.1557 |
100505854 | APTR | A001-C-108 | Human | Colorectum | FAP | 3.49e-07 | -2.50e-01 | -0.0272 |
100505854 | APTR | A002-C-205 | Human | Colorectum | FAP | 1.55e-07 | -2.21e-01 | -0.1236 |
100505854 | APTR | A015-C-005 | Human | Colorectum | FAP | 1.41e-04 | -2.45e-01 | -0.0336 |
100505854 | APTR | A015-C-006 | Human | Colorectum | FAP | 5.45e-06 | -2.58e-01 | -0.0994 |
100505854 | APTR | A015-C-106 | Human | Colorectum | FAP | 1.14e-03 | -2.29e-01 | -0.0511 |
100505854 | APTR | A002-C-114 | Human | Colorectum | FAP | 1.72e-06 | -2.44e-01 | -0.1561 |
100505854 | APTR | A015-C-104 | Human | Colorectum | FAP | 1.72e-10 | -2.87e-01 | -0.1899 |
100505854 | APTR | A001-C-014 | Human | Colorectum | FAP | 2.80e-05 | -2.67e-01 | 0.0135 |
100505854 | APTR | A002-C-016 | Human | Colorectum | FAP | 7.26e-10 | -2.60e-01 | 0.0521 |
100505854 | APTR | A015-C-002 | Human | Colorectum | FAP | 5.04e-04 | -2.46e-01 | -0.0763 |
100505854 | APTR | A001-C-203 | Human | Colorectum | FAP | 8.86e-03 | -1.67e-01 | -0.0481 |
100505854 | APTR | A002-C-116 | Human | Colorectum | FAP | 8.50e-07 | -2.56e-01 | -0.0452 |
100505854 | APTR | A014-C-008 | Human | Colorectum | FAP | 5.65e-05 | -2.57e-01 | -0.191 |
100505854 | APTR | A018-E-020 | Human | Colorectum | FAP | 1.72e-06 | -2.02e-01 | -0.2034 |
Page: 1 2 3 4 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |