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Gene: APOA1BP |
Gene summary for APOA1BP |
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Gene information | Species | Human | Gene symbol | APOA1BP | Gene ID | 128240 |
Gene name | NAD(P)HX epimerase | |
Gene Alias | AIBP | |
Cytomap | 1q22 | |
Gene Type | protein-coding | GO ID | GO:0001525 | UniProtAcc | Q8NCW5 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
128240 | APOA1BP | P1T-E | Human | Esophagus | ESCC | 8.60e-33 | 1.30e+00 | 0.0875 |
128240 | APOA1BP | P2T-E | Human | Esophagus | ESCC | 6.78e-98 | 1.71e+00 | 0.1177 |
128240 | APOA1BP | P4T-E | Human | Esophagus | ESCC | 6.76e-78 | 2.13e+00 | 0.1323 |
128240 | APOA1BP | P5T-E | Human | Esophagus | ESCC | 2.53e-99 | 2.17e+00 | 0.1327 |
128240 | APOA1BP | P8T-E | Human | Esophagus | ESCC | 6.76e-78 | 1.24e+00 | 0.0889 |
128240 | APOA1BP | P9T-E | Human | Esophagus | ESCC | 1.25e-76 | 1.95e+00 | 0.1131 |
128240 | APOA1BP | P10T-E | Human | Esophagus | ESCC | 6.78e-98 | 1.58e+00 | 0.116 |
128240 | APOA1BP | P11T-E | Human | Esophagus | ESCC | 5.79e-50 | 1.76e+00 | 0.1426 |
128240 | APOA1BP | P12T-E | Human | Esophagus | ESCC | 7.65e-86 | 1.35e+00 | 0.1122 |
128240 | APOA1BP | P15T-E | Human | Esophagus | ESCC | 2.81e-93 | 2.05e+00 | 0.1149 |
128240 | APOA1BP | P16T-E | Human | Esophagus | ESCC | 3.86e-76 | 1.30e+00 | 0.1153 |
128240 | APOA1BP | P17T-E | Human | Esophagus | ESCC | 9.27e-45 | 1.44e+00 | 0.1278 |
128240 | APOA1BP | P19T-E | Human | Esophagus | ESCC | 1.48e-28 | 2.01e+00 | 0.1662 |
128240 | APOA1BP | P20T-E | Human | Esophagus | ESCC | 2.36e-92 | 1.71e+00 | 0.1124 |
128240 | APOA1BP | P21T-E | Human | Esophagus | ESCC | 1.16e-122 | 2.47e+00 | 0.1617 |
128240 | APOA1BP | P22T-E | Human | Esophagus | ESCC | 8.09e-141 | 2.51e+00 | 0.1236 |
128240 | APOA1BP | P23T-E | Human | Esophagus | ESCC | 1.60e-91 | 2.14e+00 | 0.108 |
128240 | APOA1BP | P24T-E | Human | Esophagus | ESCC | 9.07e-107 | 2.18e+00 | 0.1287 |
128240 | APOA1BP | P26T-E | Human | Esophagus | ESCC | 2.53e-99 | 1.90e+00 | 0.1276 |
128240 | APOA1BP | P27T-E | Human | Esophagus | ESCC | 3.86e-76 | 1.33e+00 | 0.1055 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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