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Gene: ANKRD40CL |
Gene summary for ANKRD40CL |
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Gene information | Species | Human | Gene symbol | ANKRD40CL | Gene ID | 55018 |
Gene name | ANKRD40 C-terminal like | |
Gene Alias | C17orf73 | |
Cytomap | 17q21.33 | |
Gene Type | protein-coding | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
55018 | ANKRD40CL | HTA11_2487_2000001011 | Human | Colorectum | SER | 1.03e-09 | 2.83e-01 | -0.1808 |
55018 | ANKRD40CL | HTA11_1938_2000001011 | Human | Colorectum | AD | 1.67e-02 | 1.39e-01 | -0.0811 |
55018 | ANKRD40CL | HTA11_78_2000001011 | Human | Colorectum | AD | 2.02e-04 | 1.60e-01 | -0.1088 |
55018 | ANKRD40CL | HTA11_347_2000001011 | Human | Colorectum | AD | 1.02e-14 | 2.87e-01 | -0.1954 |
55018 | ANKRD40CL | HTA11_2112_2000001011 | Human | Colorectum | SER | 1.08e-06 | 4.24e-01 | -0.2196 |
55018 | ANKRD40CL | HTA11_3361_2000001011 | Human | Colorectum | AD | 3.26e-04 | 1.69e-01 | -0.1207 |
55018 | ANKRD40CL | HTA11_83_2000001011 | Human | Colorectum | SER | 1.79e-04 | 2.71e-01 | -0.1526 |
55018 | ANKRD40CL | HTA11_696_2000001011 | Human | Colorectum | AD | 8.94e-11 | 2.39e-01 | -0.1464 |
55018 | ANKRD40CL | HTA11_866_2000001011 | Human | Colorectum | AD | 9.32e-10 | 2.05e-01 | -0.1001 |
55018 | ANKRD40CL | HTA11_1391_2000001011 | Human | Colorectum | AD | 9.45e-06 | 2.07e-01 | -0.059 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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