TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
ZNF429 | ICAF | Breast | IDC | ZNF431,PMP22,CDKN2C, etc. | 6.02e-03 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Breast/Str/TF_IDC/regulons_activity_in_dotplot.png) |
ZNF429 | NK | Lung | AAH | HMGB1,RHOH,TMEM267, etc. | 9.91e-03 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_AAH/regulons_activity_in_dotplot.png) |
ZNF429 | PERI | Oral cavity | ADJ | RNF175,FAM150B,AC009501.4, etc. | 4.29e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/OralCavity/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF429 | MSC.MVA | Oral cavity | ADJ | RNF175,FAM150B,AC009501.4, etc. | 1.12e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/OralCavity/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF429 | FIB | Oral cavity | OSCC | RNF175,FAM150B,AC009501.4, etc. | 0.00e+00 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/OralCavity/Str/TF_OSCC/regulons_activity_in_dotplot.png) |
ZNF429 | CAF | Oral cavity | OSCC | RNF175,FAM150B,AC009501.4, etc. | 0.00e+00 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/OralCavity/Str/TF_OSCC/regulons_activity_in_dotplot.png) |
ZNF429 | MYOFIB | Stomach | ADJ | BMP5,SRPX,DTNA, etc. | 1.95e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Stomach/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF429 | ICAF | Stomach | ADJ | BMP5,SRPX,DTNA, etc. | 2.46e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Stomach/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF429 | MYOFIB | Stomach | CAG with IM | BMP5,SRPX,DTNA, etc. | 1.40e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Stomach/Str/TF_CAG with IM/regulons_activity_in_dotplot.png) |
ZNF429 | SMC | Stomach | CSG | BMP5,SRPX,DTNA, etc. | 2.52e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Stomach/Str/TF_CSG/regulons_activity_in_dotplot.png) |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZNF429 | SNV | Missense_Mutation | novel | c.1814N>T | p.Ser605Phe | p.S605F | Q86V71 | protein_coding | tolerated(0.36) | possibly_damaging(0.67) | TCGA-BA-A6DA-01 | Oral cavity | head & neck squamous cell carcinoma | Female | <65 | I/II | Chemotherapy | cisplatin | CR |
ZNF429 | SNV | Missense_Mutation | novel | c.2020N>T | p.Gly674Cys | p.G674C | Q86V71 | protein_coding | deleterious_low_confidence(0) | possibly_damaging(0.669) | TCGA-CN-5356-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | III/IV | Unknown | Unknown | SD |
ZNF429 | SNV | Missense_Mutation | rs779776849 | c.740N>G | p.His247Arg | p.H247R | Q86V71 | protein_coding | deleterious(0.01) | probably_damaging(0.974) | TCGA-CN-5366-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | I/II | Chemotherapy | unknown | PD |
ZNF429 | SNV | Missense_Mutation | novel | c.368N>A | p.Cys123Tyr | p.C123Y | Q86V71 | protein_coding | tolerated(0.12) | benign(0.007) | TCGA-CN-A6V1-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | I/II | Immunotherapy | erbitux | CR |
ZNF429 | SNV | Missense_Mutation | novel | c.1789N>C | p.Glu597Gln | p.E597Q | Q86V71 | protein_coding | tolerated(0.06) | benign(0.011) | TCGA-CR-6484-01 | Oral cavity | head & neck squamous cell carcinoma | Female | >=65 | I/II | Chemotherapy | carboplatin | SD |
ZNF429 | SNV | Missense_Mutation | rs764139712 | c.86A>G | p.Tyr29Cys | p.Y29C | Q86V71 | protein_coding | deleterious(0) | probably_damaging(1) | TCGA-CV-7446-01 | Oral cavity | head & neck squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | PD |
ZNF429 | insertion | Frame_Shift_Ins | rs745818467 | c.799_800insCATCT | p.Ser267ThrfsTer41 | p.S267Tfs*41 | Q86V71 | protein_coding | | | TCGA-HD-8634-01 | Oral cavity | head & neck squamous cell carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF429 | SNV | Missense_Mutation | rs368726828 | c.1988G>A | p.Arg663Gln | p.R663Q | Q86V71 | protein_coding | tolerated_low_confidence(0.38) | benign(0.061) | TCGA-XK-AAIW-01 | Prostate | prostate adenocarcinoma | Male | >=65 | 9 | Unknown | Unknown | PD |
ZNF429 | SNV | Missense_Mutation | rs771900629 | c.1391N>A | p.Arg464Gln | p.R464Q | Q86V71 | protein_coding | tolerated(1) | benign(0.005) | TCGA-B7-A5TI-01 | Stomach | stomach adenocarcinoma | Male | <65 | III/IV | Chemotherapy | eloxatin | CR |
ZNF429 | SNV | Missense_Mutation | rs368726828 | c.1988N>A | p.Arg663Gln | p.R663Q | Q86V71 | protein_coding | tolerated_low_confidence(0.38) | benign(0.061) | TCGA-B7-A5TJ-01 | Stomach | stomach adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |