GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00352643 | Liver | NAFLD | multicellular organism growth | 27/1882 | 132/18723 | 2.57e-04 | 4.19e-03 | 27 |
GO:00307055 | Liver | NAFLD | cytoskeleton-dependent intracellular transport | 33/1882 | 195/18723 | 1.98e-03 | 1.98e-02 | 33 |
GO:00109703 | Liver | NAFLD | transport along microtubule | 26/1882 | 155/18723 | 6.30e-03 | 4.69e-02 | 26 |
GO:00080884 | Liver | NAFLD | axo-dendritic transport | 15/1882 | 75/18723 | 7.02e-03 | 4.91e-02 | 15 |
GO:00017015 | Liver | Cirrhotic | in utero embryonic development | 134/4634 | 367/18723 | 2.78e-07 | 6.86e-06 | 134 |
GO:003070511 | Liver | Cirrhotic | cytoskeleton-dependent intracellular transport | 68/4634 | 195/18723 | 9.54e-04 | 6.77e-03 | 68 |
GO:003526411 | Liver | Cirrhotic | multicellular organism growth | 47/4634 | 132/18723 | 3.40e-03 | 1.89e-02 | 47 |
GO:000808811 | Liver | Cirrhotic | axo-dendritic transport | 29/4634 | 75/18723 | 5.24e-03 | 2.69e-02 | 29 |
GO:00109701 | Liver | Cirrhotic | transport along microtubule | 52/4634 | 155/18723 | 8.42e-03 | 3.91e-02 | 52 |
GO:000170111 | Liver | HCC | in utero embryonic development | 204/7958 | 367/18723 | 2.44e-07 | 4.30e-06 | 204 |
GO:00080882 | Liver | HCC | axo-dendritic transport | 52/7958 | 75/18723 | 2.34e-06 | 3.14e-05 | 52 |
GO:003070521 | Liver | HCC | cytoskeleton-dependent intracellular transport | 111/7958 | 195/18723 | 3.25e-05 | 3.28e-04 | 111 |
GO:00109702 | Liver | HCC | transport along microtubule | 90/7958 | 155/18723 | 6.49e-05 | 5.92e-04 | 90 |
GO:003526421 | Liver | HCC | multicellular organism growth | 70/7958 | 132/18723 | 9.29e-03 | 3.57e-02 | 70 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
APBA1 | SNV | Missense_Mutation | novel | c.1160C>A | p.Pro387His | p.P387H | Q02410 | protein_coding | deleterious(0) | probably_damaging(0.998) | TCGA-51-6867-01 | Lung | lung squamous cell carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
APBA1 | SNV | Missense_Mutation | novel | c.837N>C | p.Gln279His | p.Q279H | Q02410 | protein_coding | deleterious_low_confidence(0.02) | benign(0.201) | TCGA-66-2769-01 | Lung | lung squamous cell carcinoma | Male | >=65 | III/IV | Unknown | Unknown | SD |
APBA1 | SNV | Missense_Mutation | rs374176608 | c.1679N>A | p.Arg560His | p.R560H | Q02410 | protein_coding | deleterious(0.01) | probably_damaging(0.989) | TCGA-85-8287-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
APBA1 | SNV | Missense_Mutation | novel | c.2008N>T | p.Val670Leu | p.V670L | Q02410 | protein_coding | deleterious(0.02) | possibly_damaging(0.553) | TCGA-96-8169-01 | Lung | lung squamous cell carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
APBA1 | SNV | Missense_Mutation | novel | c.97N>A | p.Glu33Lys | p.E33K | Q02410 | protein_coding | deleterious_low_confidence(0.01) | benign(0.017) | TCGA-CN-4723-01 | Oral cavity | head & neck squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
APBA1 | SNV | Missense_Mutation | novel | c.2267N>C | p.Arg756Pro | p.R756P | Q02410 | protein_coding | deleterious(0) | probably_damaging(0.933) | TCGA-CN-4725-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
APBA1 | SNV | Missense_Mutation | novel | c.1106N>G | p.Tyr369Cys | p.Y369C | Q02410 | protein_coding | deleterious(0.05) | probably_damaging(0.997) | TCGA-CN-A63W-01 | Oral cavity | head & neck squamous cell carcinoma | Female | <65 | I/II | Chemotherapy | vectibix | CR |
APBA1 | SNV | Missense_Mutation | novel | c.1655N>A | p.Gly552Glu | p.G552E | Q02410 | protein_coding | deleterious(0.01) | probably_damaging(1) | TCGA-CV-5439-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | I/II | Chemotherapy | carboplatin | PD |
APBA1 | SNV | Missense_Mutation | | c.1040C>T | p.Ser347Leu | p.S347L | Q02410 | protein_coding | deleterious(0) | benign(0.006) | TCGA-CV-5442-01 | Oral cavity | head & neck squamous cell carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
APBA1 | SNV | Missense_Mutation | novel | c.574G>A | p.Gly192Ser | p.G192S | Q02410 | protein_coding | tolerated_low_confidence(0.11) | possibly_damaging(0.486) | TCGA-CV-6933-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | III/IV | Unknown | Unknown | SD |