Tissue | Expression Dynamics | Abbreviation |
Colorectum (GSE201348) | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Colorectum/Becker/ABI3BP_pca_on_diff_genes.png) | FAP: Familial adenomatous polyposis |
CRC: Colorectal cancer |
Colorectum (HTA11) | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Colorectum/Chen/ABI3BP_pca_on_diff_genes.png) | AD: Adenomas |
SER: Sessile serrated lesions |
MSI-H: Microsatellite-high colorectal cancer |
MSS: Microsatellite stable colorectal cancer |
Esophagus | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Esophagus/ABI3BP_pca_on_diff_genes.png) | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias |
LGIN: Low-grade intraepithelial neoplasias |
Thyroid | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Thyroid/ABI3BP_pca_on_diff_genes.png) | ATC: Anaplastic thyroid cancer |
HT: Hashimoto's thyroiditis |
PTC: Papillary thyroid cancer |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ABI3BP | SNV | Missense_Mutation | | c.336N>T | p.Lys112Asn | p.K112N | Q7Z7G0 | protein_coding | deleterious(0) | possibly_damaging(0.811) | TCGA-B5-A1MR-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | III/IV | Unknown | Unknown | SD |
ABI3BP | SNV | Missense_Mutation | novel | c.2956A>G | p.Arg986Gly | p.R986G | Q7Z7G0 | protein_coding | deleterious(0) | probably_damaging(0.995) | TCGA-B5-A1MX-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Hormone Therapy | megace | SD |
ABI3BP | SNV | Missense_Mutation | novel | c.659N>C | p.Val220Ala | p.V220A | Q7Z7G0 | protein_coding | deleterious(0.01) | benign(0.199) | TCGA-B5-A3FA-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ABI3BP | SNV | Missense_Mutation | rs778719617 | c.1516A>G | p.Thr506Ala | p.T506A | Q7Z7G0 | protein_coding | tolerated(0.33) | benign(0.068) | TCGA-B5-A3FC-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ABI3BP | SNV | Missense_Mutation | rs751074977 | c.998G>A | p.Arg333Gln | p.R333Q | Q7Z7G0 | protein_coding | tolerated(1) | benign(0) | TCGA-B5-A3FC-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ABI3BP | SNV | Missense_Mutation | | c.1084N>A | p.Ala362Thr | p.A362T | Q7Z7G0 | protein_coding | deleterious(0.01) | benign(0.185) | TCGA-BG-A0M4-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Chemotherapy | carboplatin | SD |
ABI3BP | SNV | Missense_Mutation | novel | c.496C>T | p.Arg166Cys | p.R166C | Q7Z7G0 | protein_coding | deleterious(0) | probably_damaging(0.997) | TCGA-BK-A6W3-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ABI3BP | SNV | Missense_Mutation | novel | c.1676N>A | p.Pro559His | p.P559H | Q7Z7G0 | protein_coding | deleterious(0.01) | possibly_damaging(0.681) | TCGA-BS-A0UF-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ABI3BP | SNV | Missense_Mutation | rs553697655 | c.1238G>A | p.Arg413His | p.R413H | Q7Z7G0 | protein_coding | tolerated(0.17) | benign(0) | TCGA-D1-A103-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ABI3BP | SNV | Missense_Mutation | rs761330735 | c.313C>A | p.Pro105Thr | p.P105T | Q7Z7G0 | protein_coding | deleterious(0) | probably_damaging(0.998) | TCGA-D1-A16J-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Chemotherapy | carboplatin | SD |